Evidence map›Paper›PMID 42737607›Full record

ArticleInternational journal of molecular sciences2026

Wenzhuo Ma, Clarissa Cavarsan, Lauren F Bazinet, Scarlett M Silvia, Joseph Owusu-Sarfo, Janet Atoyan, Judianne Davis, William E Van Nostrand, John K Robinson, Richard T Clements

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wenzhuo MaDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0001-8670-0662
Clarissa CavarsanDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0002-6687-2130
Lauren F BazinetDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
Scarlett M SilviaDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
Joseph Owusu-SarfoDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0002-5304-3480
Janet AtoyanDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
Judianne DavisDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
William E Van NostrandDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0002-0660-2825
John K RobinsonDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.
Richard T ClementsDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.

Funding

Training CoreP20GM103430 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI Christopher Lee Hemme · 2012 to 2026
$63.6M
Supplement for Google cloud build-outR24GM137786 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Alan Tackett · 2020 to 2026
$15.4M
Surgical Cardioprotection Through BKCa-Dependent Modulation of Mitochondrial SupercomplexesR01HL135236 · NHLBI · UNIVERSITY OF RHODE ISLAND · PI CLEMENTS, RICHARD T · 2018 to 2021
$1.9M
NHLBI NIH HHS R01 HL135236NIGMS NIH HHS P20 GM103430NIGMS NIH HHS R24 GM137786NIH HHS 5R01HL135236-02
6 · The paper itself

Abstract

Mitochondrial dysfunction, including impaired respiration and increased reactive oxygen species (ROS), is an early feature of Alzheimer's disease (AD) models. Electron transport chain supercomplexes (mSCs) regulate respiratory efficiency and ROS generation, yet genetic determinants of mSC organization in AD models remain underappreciated. Cox7a2l is known to promote CIII

Indexed as

Alzheimer DiseaseElectron Transport Complex IIIElectron Transport Complex IVMitochondriaAnimalsDisease Models, AnimalMiceMice, Inbred C57BLMice, TransgenicRatsReactive Oxygen SpeciesElectron Transport Complex IIIElectron Transport Complex IVReactive Oxygen SpeciesAlzheimer’s diseaseCOX7RPmitochondrial supercomplexrespirationSCAF1supercomplex

Identifiers

PMID42737607
PMCPMC13566326

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.