Evidence map›Paper›PMID 42737580›Full record

ArticleInternational journal of molecular sciences2026

Gelatin Hydrolysate from Bigeye Snapper (

Krit Jaikumkao, Khin Thandar Htun, Nattavadee Pengrattanachot, Prempree Sutthasupha, Sasivimon Promsan, Napatsorn Montha, Onanong Jaruan, Rarin Suriyalungka, Phassaraporn Khadtha, Sompong Sriburee and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Krit JaikumkaoDepartment of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-5087-680X
Khin Thandar HtunCenter of Radiation Research and Medical Imaging, Department of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-2447-502X
Nattavadee PengrattanachotDepartment of Physiology, Faculty of Medicine, Kasetsart University, Bangkok 10900, Thailand.
Prempree SutthasuphaRenal Transporter and Molecular Signaling Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Sasivimon PromsanDivision of Physiology, School of Medical Sciences, University of Phayao, Phayao 56000, Thailand.ORCID 0000-0001-8771-7108
Napatsorn MonthaDepartment of Animal and Aquatic Science, Faculty of Agriculture, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0009-0004-9688-9293
Onanong JaruanRenal Transporter and Molecular Signaling Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Rarin SuriyalungkaDepartment of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Phassaraporn KhadthaDepartment of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.
Sompong SribureeDepartment of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0009-0000-0782-326X
Suchart KothanDepartment of Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0001-7390-8878
Sutee WangtueaiSchool of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.ORCID 0000-0001-5811-1721
Anusorn LungkaphinRenal Transporter and Molecular Signaling Unit, Department of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0003-4522-0026

Funding

Functional Food Research Center for Well-Being, Multidisciplinary Research Institute, Chiang Mai University.Functional Foods for Health and Disease, Faculty of Medicine, Chiang Mai UniversityFundamental Fund 2023, Chiang Mai UniversityNational Research Council of Thailand (NRCT) and Chiang Mai University N42A650306Office of the Permanent Secretary, Ministry of Higher Education, Science, Research and Innovation, Thailand Science Research and Innovation RGNS 64-053
6 · The paper itself

Abstract

Diabetic nephropathy (DN) is a major complication of chronic hyperglycemia. Although fish gelatin hydrolysate has antioxidant, anti-inflammatory, and antihypertensive properties, its renoprotective effects in DN remain unclear. This study investigated its effects on renal oxidative stress, inflammation, fibrosis, and endoplasmic reticulum (ER) stress in diabetic rats. Thirty male Wistar rats were fed a normal chow diet or a high-fat diet for 4 weeks. Diabetes was induced in high-fat-diet-fed rats by a single intraperitoneal injection of streptozotocin (30 mg/kg). Diabetic rats were randomly assigned to receive no treatment (untreated diabetes), gelatin hydrolysate at 250 or 500 mg/day, or metformin at 100 mg/kg/day groups (

Indexed as

Diabetic NephropathiesEndoplasmic Reticulum StressGelatinOxidative StressProtein HydrolysatesAnimalsDiabetes Mellitus, ExperimentalDiet, High-FatDisease ProgressionFibrosisInflammationKidneyMaleRatsRats, WistarSignal TransductionGelatinProtein Hydrolysatesdiabetic nephropathyER stressfibrosisfish gelatin hydrolysateinflammationoxidative stress

Identifiers

PMID42737580
PMCPMC13566746

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.