Evidence map›Paper›PMID 42737529›Full record

ArticleInternational journal of molecular sciences2026

Insertion-Site Proximity to AAV Inverted Terminal Repeats Increases Plasmid Recombination.

Maxim Makarenko, Daria Semicheva, Veniamin Fishman

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Maxim MakarenkoCenter for Genetics and Life Sciences, Sirius Institute of Science and Technology, Sirius 354340, Russia.
Daria SemichevaCenter for Genetics and Life Sciences, Sirius Institute of Science and Technology, Sirius 354340, Russia.
Veniamin FishmanCenter for Genetics and Life Sciences, Sirius Institute of Science and Technology, Sirius 354340, Russia.ORCID 0000-0002-5573-3100

Funding

Sirius University of Science and Technology Agreement №26-03, 27/09/2024
6 · The paper itself

Abstract

Adeno-associated virus (AAV)-based massively parallel reporter assays (MPRA) have become an important platform for large-scale functional characterization of regulatory DNA elements. However, plasmids carrying AAV inverted terminal repeats (ITRs) are intrinsically unstable during propagation in

Indexed as

DependovirusPlasmidsRecombination, GeneticTerminal Repeat SequencesCloning, MolecularEscherichia coliadeno-associated virus (AAV)inverted terminal repeats (ITRs)massively parallel reporter assay (MPRA)plasmid stabilityrecombination

Identifiers

PMID42737529
PMCPMC13566322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.