ArticleInternational journal of molecular sciences2026
Exploring Novel Indazole and Pyrazole Nucleoside Analogues: Enzymatic Synthesis, Characterization, and Biological Evaluation.
Anton F Mironov, Barbara Z Eletskaya, Konstantin V Antonov, Alexander S Paramonov, Roman S Esipov, Irina D Konstantinova, Sofya N Andreevskaya, Tatiana G Smirnova, Inna L Karpenko, Vera A Sokhraneva and 4 more
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In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
14 authors.
Anton F MironovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.ORCID 0009-0003-8943-6918 Barbara Z EletskayaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.ORCID 0000-0002-9552-7141 Konstantin V AntonovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.
Alexander S ParamonovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.ORCID 0000-0003-3614-560X Roman S EsipovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.ORCID 0000-0002-3231-5838 Irina D KonstantinovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya St. 16/10, 117997 Moscow, Russia.ORCID 0000-0001-5563-6549 Sofya N AndreevskayaMicrobiology Department, Central Tuberculosis Research Institute, 2 Yauzskaya Alley, 107564 Moscow, Russia.
Tatiana G SmirnovaMicrobiology Department, Central Tuberculosis Research Institute, 2 Yauzskaya Alley, 107564 Moscow, Russia.
Inna L KarpenkoEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.ORCID 0000-0001-9849-0447 Vera A SokhranevaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.ORCID 0000-0003-0930-5604 Iulia S ZhivotovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.
Sergey N KochetkovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.ORCID 0000-0002-7443-6961 Anastasia L KhandazhinskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.ORCID 0000-0003-1452-0253 Elena S MatyuginaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilov St. 32, 119991 Moscow, Russia.ORCID 0000-0002-4981-7316 Funding
Russian Science Foundation 24-14-00458Russian Science Foundation 25-14-00305
6 · The paper itselfAbstract
New indazole and pyrazole nucleoside analogues were synthesized by enzymatic transglycosylation using
Indexed as
IndazolesNucleosidesPurine-Nucleoside PhosphorylasePyrazolesCell Line, TumorEscherichia coliGlycosylationHumansMicrobial Sensitivity TestsModels, MolecularMycobacterium tuberculosisStructure-Activity RelationshipSubstrate SpecificityIndazolesNucleosidesPurine-Nucleoside PhosphorylasepyrazolePyrazolesantibacterial activityantituberculosis activityindazolenucleoside analoguespurine nucleoside phosphorylasepyrazole
Identifiers
PMID42737455
PMCPMC13566874
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