Evidence map›Paper›PMID 42737419›Full record

ArticleInternational journal of molecular sciences2026

Kidney Cyst Epithelia in Tuberous Sclerosis Complex (TSC) Exhibit Propagation and Expansion of A-Intercalated, but Loss of B-Intercalated and Principal Cells: The Role of FOXI1, FOXP1, and DMRT2 Transcription Factors.

Manoocher Soleimani, Kamyar Zahedi, Marybeth Brooks, Julie G In, Sharon Barone

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manoocher SoleimaniResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0003-4909-4469
Kamyar ZahediResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0002-4257-5107
Marybeth BrooksResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0001-6582-2281
Julie G InDepartment of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM 87106, USA.
Sharon BaroneResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0001-5710-292X

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
Heavy metals exposure regulates secretory lineage in intestinal injuryR01ES034400 · NIEHS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Julie Goeun In · 2024 to 2026
$1.1M
BLRD VA I01 BX001000Dialysis Clinic, Inc. C-4149NCI NIH HHS P30 CA118100NIEHS NIH HHS R01 ES034400United States Department of Defense TS240031United States Department of Veterans Affairs 5I01BX001000-13
6 · The paper itself

Abstract

Kidney cystic epithelium primarily comprises proliferating A-intercalated (A-IC) cells in humans and mouse models of TSC. These studies explored the expression of transcription factors (TF) that drive the development of A-IC cells and the downregulation of B-intercalated (B-IC) cells, as well as the status and localization of

Indexed as

DNA-Binding ProteinsForkhead Transcription FactorsRepressor ProteinsTranscription FactorsTuberous SclerosisAnimalsDisease Models, AnimalEpithelial CellsHumansKidneyMiceTuberous Sclerosis Complex 1 ProteinTuberous Sclerosis Complex 2 ProteinDNA-Binding ProteinsForkhead Transcription FactorsFoxp1 protein, mouseRepressor ProteinsTranscription FactorsTuberous Sclerosis Complex 1 ProteinTuberous Sclerosis Complex 2 ProteinA-Intercalated cellscystogenesisDMRT2FOXI1FOXP1kidneytranscription factorstuberous sclerosis complex

Identifiers

PMID42737419
PMCPMC13565657

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.