Evidence map›Paper›PMID 42737417›Full record

ArticleInternational journal of molecular sciences2026

Targeting Glycolysis May Bridge Innate and Adaptive Immune Regulation in Experimental Peri-Implantitis.

Shudan Deng, Xingchen Liu, Feiyang Wu, Shoucheng Chen, Zhuofan Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shudan DengHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0001-9684-052X
Xingchen LiuHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Feiyang WuHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.
Shoucheng ChenHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.ORCID 0000-0003-0154-220X
Zhuofan ChenHospital of Stomatology, Sun Yat-sen University, Guangzhou 510055, China.

Funding

Academy of Osseointegration 50000 dollarsChina Foundation for Oral Disease Prevention and Treatment 200000 CNY
6 · The paper itself

Abstract

Peri-implantitis is characterized by progressive tissue destruction accompanied by dysregulated innate and adaptive immune responses. This study evaluated whether systemic treatment with 2-deoxy-D-glucose (2-DG) could attenuate experimental peri-implantitis and alter inflammatory markers associated with macrophage- and T-cell-mediated responses in a rat model. Experimental peri-implantitis was induced in

Indexed as

Adaptive ImmunityDeoxyglucoseImmunity, InnatePeri-ImplantitisAnimalsDisease Models, AnimalMalePorphyromonas gingivalisRatsRats, Sprague-DawleyDeoxyglucose2-deoxy-D-glucoseimmunomodulationM1-associated markersperi-implantitisTh17-associated markers

Identifiers

PMID42737417
PMCPMC13566337

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.