ArticleFoods (Basel, Switzerland)2026
Combined Protective Effects of Raffinose and Isoflavones Against High-Fructose-Induced Liver Damage via Improved Bioavailability and Metabolic Regulation.
Yingmei Wu, Xiangnan Zhang, Yu Wang, Ting Li, Yalong Lu, Xingbin Yang
Abstract read
In one paragraphArticle in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
6 authors.
Yingmei WuShaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Shaanxi Key Laboratory for Hazard Factors Assessment in Processing and Storage of Agricultural Products, Engineering Research Center of High-Valued Utilization of Fruit Resources in Western China, Ministry of Education, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, China.
Xiangnan ZhangShaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Shaanxi Key Laboratory for Hazard Factors Assessment in Processing and Storage of Agricultural Products, Engineering Research Center of High-Valued Utilization of Fruit Resources in Western China, Ministry of Education, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, China.ORCID 0009-0008-0979-7788 Yu WangShaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Shaanxi Key Laboratory for Hazard Factors Assessment in Processing and Storage of Agricultural Products, Engineering Research Center of High-Valued Utilization of Fruit Resources in Western China, Ministry of Education, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, China.
Ting LiShaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Shaanxi Key Laboratory for Hazard Factors Assessment in Processing and Storage of Agricultural Products, Engineering Research Center of High-Valued Utilization of Fruit Resources in Western China, Ministry of Education, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, China.ORCID 0000-0002-4957-6014 Yalong LuShaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Shaanxi Key Laboratory for Hazard Factors Assessment in Processing and Storage of Agricultural Products, Engineering Research Center of High-Valued Utilization of Fruit Resources in Western China, Ministry of Education, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, China.
Xingbin YangShaanxi Engineering Laboratory for Food Green Processing and Safety Control, and Shaanxi Key Laboratory for Hazard Factors Assessment in Processing and Storage of Agricultural Products, Engineering Research Center of High-Valued Utilization of Fruit Resources in Western China, Ministry of Education, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710119, China.
Funding
National Natural Science Foundation of China 32072175National Natural Science Foundation of China 32372340National Natural Science Foundation of China 32502233Postdoctoral Science Foundation of Shaanxi Province 2025BSHSDZZ237the Development Program for Innovative Research Team of Shaanxi Normal University GK202402005the key research and development plan in Shaanxi province 2022QFY09-06the key research and development plan in Shaanxi province 2024NC-GJHX-03Xi'an Agricultural Technology Research and Development Project 22NYYF046Xi'an Association for Science and Technology 0959202613161
6 · The paper itselfAbstract
This study investigated the combined administration of raffinose (RAF) and isoflavones (ISO) to enhance ISO bioavailability and alleviate high-fructose (HF)-induced liver damage. Mice were administered 20% HF water with RAF, ISO, or their combination (RAF + ISO) for 10 weeks. UPLC-qTOP/MS analysis showed that RAF + ISO significantly increased total ISO levels in serum, urine, and feces by 18.5%, 37.4%, and 13.6%, respectively, compared to ISO alone (
Indexed as
absorptiondyslipidemialiver protectionraffinosesoybean isoflavones
Identifiers
PMID42737338
PMCPMC13564495
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