Mechanism of Malondialdehyde-Induced Deterioration in Water-Holding Capacity of Bovine Myofibrillar Proteins: Insights from Structural Modifications and Molecular Docking.

He Li, Zhenyu Fang, Qin Wu, Dunhua Liu, Jun Liu, Ningxia Bu

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

He LiCollege of Life Sciences, Hubei Normal University, Huangshi 435002, China.

Zhenyu FangCollege of Life Sciences, Hubei Normal University, Huangshi 435002, China.

Qin WuCollege of Life Sciences, Hubei Normal University, Huangshi 435002, China.

Dunhua LiuCollege of Food Science and Engineering, Ningxia University, Yinchuan 750021, China.

Jun LiuCollege of Life Sciences, Hubei Normal University, Huangshi 435002, China.

Ningxia BuNingxia Veterinary Drugs and Fodder Inspection Institute, Yinchuan 750011, China.

Funding

Hubei Normal University HS2023RC084Science and Technology Department of Hubei Province 2025CSA104Science and Technology Department of Hubei Province 2025EIA078Science and Technology Department of Ningxia 2026AAC030681

6 · The paper itself

Abstract

Lipid peroxidation products can induce oxidative modification of myofibrillar proteins (MPs), thereby compromising their water-holding capacity (WHC), but the underlying molecular mechanism remains unclear. This study systematically investigated the mechanism of MDA-induced WHC deterioration in bovine myofibrillar proteins (MPs) using multispectral techniques, redox proteomics, and molecular docking. Results demonstrated that low MDA concentrations caused relatively limited water release. Structural alterations became evident at 2 mM, whereas pronounced WHC deterioration occurred at 5-10 mM. At these higher concentrations, centrifugal loss increased by up to 48.80%, and immobilized water migrated to free water (

Indexed as

cysteinelipid oxidation productsoxidation modificationprotein structurewater mobility

Identifiers

PMID42737266

DOI10.3390/foods15173022

PMCPMC13564944

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.