Evidence map›Paper›PMID 42737205›Full record

ArticleFoods (Basel, Switzerland)2026

Combined Inhibition of Polyphenol Oxidase by Oxyresveratrol and Epigallocatechin Gallate: A Natural Anti-Browning Strategy for Fresh-Cut Pears.

Ruobing Liu, Zhiqiang Ren, Nuoran Rong, Jingyu Wei, Xiaoyan Zhang, Yong Peng

Abstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruobing LiuCollege of Food Science and Engineering, Shandong Agricultural University, 61 Daizong Road, Tai'an 271018, China.
Zhiqiang RenCollege of Food Science and Engineering, Shandong Agricultural University, 61 Daizong Road, Tai'an 271018, China.
Nuoran RongCollege of Food Science and Engineering, Shandong Agricultural University, 61 Daizong Road, Tai'an 271018, China.
Jingyu WeiCollege of Food Science and Engineering, Shandong Agricultural University, 61 Daizong Road, Tai'an 271018, China.
Xiaoyan ZhangCollege of Food Science and Engineering, Shandong Agricultural University, 61 Daizong Road, Tai'an 271018, China.
Yong PengCollege of Food Science and Engineering, Shandong Agricultural University, 61 Daizong Road, Tai'an 271018, China.ORCID 0000-0003-4509-6432

Funding

Key R&D Program of Shandong Province, China 2023TZXD026National Natural Science Foundation of China 32302178Shandong Provincial Natural Science Foundation ZR2022MC102
6 · The paper itself

Abstract

Polyphenol oxidase (PPO) is a key enzyme responsible for enzymatic browning in fresh-cut fruits and vegetables, severely compromising their quality and shelf life. This study aimed to investigate the combined inhibitory mechanism of oxyresveratrol (OXY) and epigallocatechin gallate (EGCG) on PPO through multi-spectroscopic analyses, molecular docking, TEM, and XRD, with the goal of developing a natural and effective anti-browning strategy for fresh-cut fruits. The results showed that the optimal combined effect was achieved at an OXY:EGCG ratio of 1:2, where the inhibition rate was significantly enhanced by 43.72% and 14.36% compared to using OXY or EGCG single treatment, respectively. The combined treatment exhibited enhanced chelation capacity of copper ion and DPPH radical scavenging activity, and enhanced hydrogen-bonding interactions while lowering binding energy, exhibiting characteristics of mixed inhibition kinetics. Structural characterization showed that the combined treatment drastically reduced the enzyme's fluorescence intensity to 39.81% of that of the native enzyme, induced rearrangements in α-helix and random coil structures, triggered obvious protein aggregation, and weakened the intensity of crystal diffraction peaks. Importantly, the combined treatment effectively delayed browning in fresh-cut pear slices, demonstrating its practical application potential. These findings provide a promising natural combined approach for controlling enzymatic browning and extending the shelf life of fresh-cut produce.

Indexed as

conformational changeenzymatic browningfresh-cut produceinhibition ratemolecular docking

Identifiers

PMID42737205
PMCPMC13565238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.