Obesity, Insulin Resistance, and Infertility in Women with Polyendocrine Metabolic Ovarian Syndrome: A Retrospective Cohort Study at a Tertiary Referral Medical Center in Qatar.

Tahani Ibrahim Alotoum, Husam Qush, Rafea Muftah AlGhanem, Ayman El-Menyar

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Article in Healthcare (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 authors.

Tahani Ibrahim AlotoumDepartment of Obstetrics and Gynecology, Military Medical City Hospital, Doha, 2352, Qatar.

Husam QushDepartment of Obstetrics and Gynecology, Military Medical City Hospital, Doha, 2352, Qatar.

Rafea Muftah AlGhanemDepartment of Family Medicine, Military Medical City Hospital, Doha, 2352, Qatar.

Ayman El-MenyarHamad Medical Corporation, Doha P.O. Box 3050, Qatar.ORCID 0000-0003-2584-953X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsThis was a retrospective observational cohort study conducted at the Military Medical Specialist Center in Qatar (2019-2024). Data were extracted from patient medical records, including demographic characteristics, clinical presentation, hormonal profiles, metabolic parameters, and details of fertility treatment. Women aged 18-40 years diagnosed with PMOS according to the Rotterdam criteria were included. Correlation coefficient analysis was performed to assess the associations between PMOS-related factors. Patients were categorized by BMI (normal, overweight, and obese).

resultsThe mean age of patients was 31.9 ± 5.3 years, and 43.8% of patients were obese. Primary infertility was more frequent than secondary infertility (61.8% vs. 38.2%). Women with secondary infertility were significantly older and had higher body mass index (BMI) (

resultsThe mean age of patients was 31.9 ± 5.3 years, and 43.8% of patients were obese. Primary infertility was more frequent than secondary infertility (61.8% vs. 38.2%). Insulin resistance was prominent (mean HOMA-IR 4.04) and increased significantly across BMI categories (3.0 in normal-weight vs. 4.8 in obese women,

Indexed as

hormonal profileinfertilityinsulin resistanceobesityPolycystic Ovary SyndromePolyendocrine Metabolic Ovarian Syndrome

Identifiers

PMID42736835

DOI10.3390/healthcare14172677

PMCPMC13565112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.