Evidence map›Paper›PMID 42736636›Full record

ArticleJournal of Alzheimer's disease : JAD2026

Cerebral perfusion correlates of domain-specific cognitive function in Alzheimer's disease and dementia with Lewy bodies.

Yume Koizumi, Yoshikazu Nakano, Mitsuyoshi Tamura, Kousuke Yamagishi, Yutaro Suzuki, Michiko Izumi, Yoshikazu Chishiki, Kenta Osawa, Shogo Furukawa, Ai Ishikawa and 6 more

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yume KoizumiDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0009-0004-7245-1182
Yoshikazu NakanoDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0000-0003-3023-3836
Mitsuyoshi TamuraDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
Kousuke YamagishiDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
Yutaro SuzukiDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0009-0007-5125-6697
Michiko IzumiDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
Yoshikazu ChishikiDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0009-0001-6877-6898
Kenta OsawaDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0009-0002-2824-6857
Shogo FurukawaDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
Ai IshikawaDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
Yoshihisa KitayamaDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
Takuro HorikoshiDepartment of Diagnostic Radiology and Radiation Oncology, Chiba University Graduate School of Medicine, Chiba, Japan.
Takashi UnoDepartment of Diagnostic Radiology and Radiation Oncology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0000-0003-4606-5662
Masahiro MoriDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0000-0002-8767-255X
Satoshi KuwabaraDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.
Shigeki HiranoDepartment of Neurology, Chiba University Graduate School of Medicine, Chiba, Japan.ORCID 0000-0003-3473-2317

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundDifferentiating Alzheimer's disease (AD) from dementia with Lewy bodies (DLB) remains challenging because of overlapping symptoms and frequent co-pathology. Although cerebral perfusion abnormalities are well described in both disorders, how domain-specific cognitive decline relates to regional perfusion patterns remains incompletely understood.ObjectiveTo investigate disease-specific associations between regional cerebral perfusion and domain-specific cognitive performance in patients with AD and DLB.MethodsAmyloid-positive patients with AD and probable patients with DLB, each with at least one abnormal neuroimaging biomarker, underwent

Indexed as

Alzheimer DiseaseBrainCerebrovascular CirculationCognitionCognition DisordersLewy Body DiseaseAgedAged, 80 and overFemaleHumansMaleNeuropsychological TestsTomography, Emission-Computed, Single-PhotonAddenbrooke's cognitive examination IIIAlzheimer's diseasecerebral perfusioncognitive functiondementia with Lewy bodiessingle-photon emission computed tomography

Identifiers

PMID42736636
PMCPMC13688342

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.