ArticleDiabetologia2026
Differential physical activity responses to diabetes risk reduction interventions according to prediabetes phenotype in at-risk individuals: pooled analysis from three randomised controlled trials.
Article in Diabetologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
aims/hypothesisEmerging research suggests that the effects of lifestyle interventions to reduce the risk of type 2 diabetes progression differ by prediabetes phenotype. We investigated whether this divergent effectiveness is accompanied by differing physical activity responses to the intervention.
methodsPooled data from three randomised controlled trials were used (n=2150), with up to 48 months annual follow-up. Participants at risk of type 2 diabetes were randomised to either: (1) usual care (control) or (2) similar interventions, in which they received structured group-based lifestyle interventions to promote increases in physical activity and other behaviours associated with diabetes risk reduction, supported by education, goal setting, pedometer use and maintenance support. Change in physical activity and glucose levels were stratified by the presence of impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT).
resultsParticipants in the group with normoglycaemia were 63 years old (mean), with a mean BMI of 29.9 kg/m CONCLUSIONS/
interpretationThe effectiveness of structured, group-based interventions with goal setting to promote physical activity differs by glycaemic status; those with IFG were least responsive. This may contribute to previously observed differences in the clinical effectiveness of diabetes prevention programmes.
Indexed as
Identifiers
42736402What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.