Evidence map›Paper›PMID 42736378›Full record

ArticleNature genetics2026

APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers's disease.

Jesper Qvist Thomassen, Hampton Leonard, Brittany Ulms, Benjamin Grenier-Boley, Sami Heikkinen, Pablo Garcia-González, Atahualapa Castillo-Morales, Masataka Kikuchi, Jungsoo Gim, Han Cao and 123 more

Abstract read
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Article in Nature genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Proteomic Signatures of ProtectedmedRxiv : the preprint server for health sciences · 2026
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  3. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

133 authors.

Jesper Qvist Thomassen *Department of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark. jesper.qvist.thomassen@regionh.dk.ORCID http://orcid.org/0000-0003-3484-9531
Hampton Leonard *Center for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.
Brittany Ulms *Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Benjamin Grenier-Boley *Université de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.
Sami Heikkinen *Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0002-6083-2402
Pablo Garcia-González *Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya (UIC), Barcelona, Spain.ORCID http://orcid.org/0000-0003-0125-5403
Atahualapa Castillo-MoralesUK Dementia Research Institute, School of Medicine, Cardiff University, Cardiff, UK.
Masataka KikuchiDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.ORCID http://orcid.org/0000-0002-9562-841X
Jungsoo GimDepartment of Biomedical Science, Chosun University, Gwangju, Republic of Korea.ORCID http://orcid.org/0000-0002-6454-9751
Han CaoDivision of Life Science, State Key Laboratory of Molecular Neuroscience and Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.ORCID http://orcid.org/0000-0001-9992-9108
Fahri KüçükaliVIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
Najaf AminNuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-8944-1771
Dabin YoonDepartment of Biomedical Science, Chosun University, Gwangju, Republic of Korea.
Itziar de RojasAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya (UIC), Barcelona, Spain.
Pilar Alvarez JerezCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.
Victoria AlvarezLaboratorio de Genética, Hospital Universitario Central de Asturias, Oviedo, Spain.ORCID http://orcid.org/0000-0002-1916-2523
Beatrice ArosioDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-0615-3580
Céline BellenguezUniversité de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.ORCID http://orcid.org/0000-0002-1240-7874
Sverre BerghThe Research Centre for Age-related Functional Decline and Disease, Innlandet Hospital Trust, Ottestad, Norway.ORCID http://orcid.org/0000-0001-9593-2967
Kimberley BillingsleyCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-8003-4029
Cornelis BlauwendraatCoalition for Aligning Science, Chevy Chase, MD, USA.
Merce BoadaAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya (UIC), Barcelona, Spain.ORCID http://orcid.org/0000-0003-2617-3009
Barbara BorroniDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Paola BossùLaboratory of Experimental Neuropsychobiology, Clinical Neuroscience and Neurorehabilitation Department, IRCCS Santa Lucia Foundation, Rome, Italy.ORCID http://orcid.org/0000-0002-1432-0078
María J BullidoNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0002-6477-1117
Antonio DanieleDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Ángel CarracedoGrupo de Medicina Xenómica, CIBERER, CIMUS, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Alexandre de MendonçaFaculty of Medicine, University of Lisbon, Lisbon, Portugal.
Mark CooksonCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-1058-3831
Jürgen DeckertDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital of Würzburg, Würzburg, Germany.ORCID http://orcid.org/0000-0003-1008-4650
Martin DichgansInstitute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.ORCID http://orcid.org/0000-0002-0654-387X
Srdjan DjurovicDepartment of Medical Genetics, Oslo University Hospital, Oslo, Norway.ORCID http://orcid.org/0000-0002-8140-8061
Oriol Dols-IcardoNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0003-2656-8748
Carole DufouilUniversity of Bordeaux, Inserm Bordeaux Population Health Research Center U1219, Bordeaux, France.ORCID http://orcid.org/0000-0003-2442-4476
Emrah DüzelGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Valentina Escott-PriceUKDRI@ Cardiff, School of Medicine, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0003-1784-5483
Tormod FladbyInstitute of Clinical Medicine, Campus Ahus, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0002-9984-9797
Laura FratiglioniKarolinska University Hospital, Theme inflammation and Aging, Stockholm, Sweden.
Amy K Y FuDivision of Life Science, State Key Laboratory of Molecular Neuroscience and Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
Daniela GalimbertiNeurodegenerative Diseases Unit, Fondazione IRCCS Ca' Granda, Ospedale Policlinico, Milan, Italy.ORCID http://orcid.org/0000-0002-9284-5953
Jose Maria García-AlbercaNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0003-2951-6644
Vilmantas GiedraitisDepartment of Public Health and Caring Sciences, Clinical Geriatrics, Uppsala University, Uppsala, Sweden.
Guillermo Garcia-RibasHospital Universitario Ramon y Cajal, IRYCIS, Madrid, Spain.
Caroline GraffKarolinska University Hospital, Theme inflammation and Aging, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-9949-2951
Timo GrimmerCenter for Cognitive Disorders, Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine, Munich, Germany.ORCID http://orcid.org/0000-0002-6829-6253
Edna GrünblattDepartment of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-8505-7265
Olivier HanonUniversité Paris Cité, EA 4468, APHP, Hospital Broca, Memory Resource and Research Centre of de Paris-Broca-Ile de France, Paris, France.
Lucrezia HausnerDepartment of Geriatric Psychiatry, Central Institute for Mental Health Mannheim, Faculty Mannheim, University of Heidelberg, Mannheim, Germany.ORCID http://orcid.org/0000-0001-9009-2356
Stefanie Heilmann-HeimbachInstitute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany.ORCID http://orcid.org/0000-0003-1057-465X
Jakub HortMemory Clinic, Department of Neurology, Charles University, Second Faculty of Medicine and Motol University Hospital, Prague, Czech Republic.ORCID http://orcid.org/0000-0002-1080-3726
Frank JessenDepartment of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Kendall JensenCenter for Noninvasive Diagnostics, TGen, Phoenix, AZ, USA.
Caroline JonsonCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.
Yoontae KimWell-aging Medicare Institute & CSU G-LAMP Project Group, Chosun University, Gwangju, Republic of Korea.ORCID http://orcid.org/0009-0008-0913-006X
Nicole KuznetsovCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.
Ville LeinonenDepartment of Neurosurgery, Kuopio University Hospital, Kuopio, Finland.ORCID http://orcid.org/0000-0002-4282-4687
Anssi LipponenInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0002-4403-9084
Jiao LuoDepartment of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Mary MakariousCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.
Henna MartiskainenInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0003-2796-1859
Carlo MasulloInstitute of Neurology, Catholic University of the Sacred Heart, Rome, Italy.
Patrizia MecocciDivision of Gerontology and Geriatrics, Department of Medicine and Surgery, University of Perugia, Perugia, Italy.ORCID http://orcid.org/0000-0003-0729-5246
Shima MehrabianClinic of Neurology, UH 'Alexandrovska', Medical University-Sofia, Sofia, Bulgaria.
Pablo MirNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0003-1656-302X
Akinori MiyashitaDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.ORCID http://orcid.org/0000-0003-2508-9649
Susanne MoebusInstitute for Urban Public Health, University Hospital of University Duisburg-Essen, Essen, Germany.ORCID http://orcid.org/0000-0002-0072-5410
Kin Y MokDivision of Life Science, State Key Laboratory of Molecular Neuroscience and Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.
Laura Molina PorcelNeurological Tissue Bank-Biobanc-Hospital Clinic-IDIBAPS, Barcelona, Spain.ORCID http://orcid.org/0000-0003-4068-8578
Fermin MorenoNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0001-5200-3164
Benedetta NacmiasDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.ORCID http://orcid.org/0000-0001-9338-9040
Lucilla ParnettiCentre for Memory Disturbances, Lab of Clinical Neurochemistry, Section of Neurology, University of Perugia, Perugia, Italy.ORCID http://orcid.org/0000-0001-5722-3967
Pau PastorFundació Docència i Recerca Mútua Terrassa, Barcelona, Spain.ORCID http://orcid.org/0000-0002-7493-8777
Jordi Pérez-TurNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0002-9111-1712
Oliver PetersGerman Center for Neurodegenerative Diseases (DZNE), Berlin, Germany.ORCID http://orcid.org/0000-0003-0568-2998
Yolande A L PijnenburgAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, the Netherlands.
Gerard Piñol-RipollUnitat Trastorns Cognitius, Hospital Universitari Santa Maria de Lleida, Lleida, Spain.
Julius PoppOld Age Psychiatry, Department of Psychiatry, Lausanne University Hospital, Lausanne, Switzerland.
Innocenzo RaineroDepartment of Neuroscience 'Rita Levi Montalcini', University of Torino, Torino, Italy.
Luis M RealUnidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.ORCID http://orcid.org/0000-0003-4932-7429
Steffi Riedel-HellerInstitute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.ORCID http://orcid.org/0000-0003-4321-6090
Eloy Rodriguez-RodriguezNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0001-7742-677X
Arvid RongveDepartment of Research and Innovation, Haugesund Hospital, Haugesund, Norway.ORCID http://orcid.org/0000-0002-0476-4134
Giacomina RossiUnit of Neurology V-Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy.ORCID http://orcid.org/0000-0001-6680-2725
Jose Luis RoyoDepatamento de Especialidades Quirúrgicas, Bioquímica e Inmunología, Facultad de Medicina, Universidad de Málaga, Málaga, Spain.
Dan RujescuDepartment of Psychiatry and Psychotherapy, Medical University Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-1432-313X
Ingvild SaltvedtDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Department of Geriatrics, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.ORCID http://orcid.org/0000-0002-7897-9808
María Eugenia SáezCAEBI, Centro Andaluz de Estudios Bioinformáticos, Sevilla, Spain.ORCID http://orcid.org/0000-0001-9299-2534
Raquel Sánchez-ValleAlzheimer's Disease and Other Cognitive Disorders Unit, Service of Neurology, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.
Florentino Sanchez-GarciaDepartment of Immunology, Hospital Universitario Doctor Negrín, Las Palmas, Spain.
Nicolai SandauDepartment of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-1941-097X
Nikolaos ScarmeasTaub Institute for Research in Alzheimer's Disease and the Aging Brain, The Gertrude H. Sergievsky Center, Depatment of Neurology, Columbia University, New York City, NY, USA.
Katja SchefflerDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Department of Geriatrics, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.ORCID http://orcid.org/0000-0002-1734-7807
Norbert ScherbaumDepartment of Psychiatry and Psychotherapy, LVR-Klinikum Essen, University of Duisburg-Essen, Essen, Germany.ORCID http://orcid.org/0000-0003-1759-6990
Anja SchneiderGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0001-9540-8700
Geir SelbækNorwegian National Advisory Unit on Aging and Health, Vestfold Health Trust, Tønsberg, Norway.ORCID http://orcid.org/0000-0001-6511-8219
Davide SeripaDepartment of Hematology and Stem Cell Transplant, Vito Fazzi Hospital, Lecce, Italy.
Vincenzo SolfrizziInterdisciplinary Department of Medicine, Geriatric Medicine and Memory Unit, University of Bari Aldo Moro, Bari, Italy.ORCID http://orcid.org/0000-0002-8524-0315
Marco SpallazziDepartment of Medicine and Surgery, Unit of Neurology, University-Hospital of Parma, Parma, Italy.
Alessio SquassinaDepartment of Biomedical Sciences, Section of Neuroscience and Clinical Pharmacology, University of Cagliari, Cagliari, Italy.ORCID http://orcid.org/0000-0001-7415-7607
Eystein StordalNamsos Hospital, Namsos, Norway.ORCID http://orcid.org/0000-0002-2443-7923
Niccoló TesiAmsterdam Neuroscience, Neurodegeneration, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-1413-5091
Lucio TremolizzoNeurology Unit, IRCCS 'San Gerardo dei Tintori', Monza, Italy.
Kumar P TripathiDivision of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Wiesje M van der FlierAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0001-8766-6224
Julie WilliamsUK Dementia Research Institute, School of Medicine, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0002-4069-0259
Jens WiltfangDepartment of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.ORCID http://orcid.org/0000-0003-1492-5330
Dag AarslandDepartment of Old Age Psychiatry, Division of Academic Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Andrew B SingletonCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA.
Philippe AmouyelUniversité de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.ORCID http://orcid.org/0000-0001-9088-234X
Stéphanie DebetteUniversity of Bordeaux, Inserm Bordeaux Population Health Research Center U1219, Bordeaux, France.ORCID http://orcid.org/0000-0001-8675-7968
Magda Tsolaki1st Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.ORCID http://orcid.org/0000-0002-2072-8010
Gael NicolasUniv Rouen Normandie, Normandie Univ, Inserm U1245 and CHU Rouen, Department of Genetics and Reference Center for Developmental Disorders, Rouen, France.ORCID http://orcid.org/0000-0001-9391-7800
Sven van der LeeAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0003-1606-8643
Henne HolstegeAlzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-7688-3087
Maria Victoria FernandezAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya (UIC), Barcelona, Spain.
Patrick Gavin KehoeBristol Medical School, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-7542-1139
Kristel SleegersVIB Center for Molecular Neurology, VIB, Antwerp, Belgium.
Martin IngelssonDepartment of Public Health and Caring Sciences, Clinical Geriatrics, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-5466-8370
Roberta GhidoniMolecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.ORCID http://orcid.org/0000-0002-7691-1957
Ole A AndreassenCentre for Precision Psychiatry, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Peter A HolmansDivision of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0003-0870-9412
Pascual Sánchez-JuanNetwork Center on Biomedical Research in Neurodegenerative Diseases (CIBERNED), National Institute of Health Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0002-6081-8037
Rebecca SimsDivision of Psychological Medicine and Clinical Neuroscience, School of Medicine, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0002-3885-1199
Nancy Y IpDivision of Life Science, State Key Laboratory of Molecular Neuroscience and Daniel and Mayce Yu Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Hong Kong, China.ORCID http://orcid.org/0000-0002-2763-8907
Kun Ho LeeDepartment of Biomedical Science, Chosun University, Gwangju, Republic of Korea.ORCID http://orcid.org/0000-0003-4144-8162
Takeshi IkeuchiDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.ORCID http://orcid.org/0000-0001-8828-8085
Alfredo RamirezGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.ORCID http://orcid.org/0000-0003-4991-763X
Agustin RuizAce Alzheimer Center Barcelona, Universitat Internacional de Catalunya (UIC), Barcelona, Spain.
Mikko HiltunenInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.ORCID http://orcid.org/0000-0003-3566-4096
Jean-Charles LambertUniversité de Lille, Inserm, CHU Lille, Institut Pasteur de Lille, Lille, France.ORCID http://orcid.org/0000-0003-0829-7817
Cornelia van DuijnNuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-2374-9204
Mike NallsCenter for Alzheimer's and Related Dementias, National Institute on Aging, Bethesda, MD, USA. mike@datatecnica.com.ORCID http://orcid.org/0000-0003-0319-4325
Ruth Frikke-SchmidtDepartment of Clinical Biochemistry, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark. ruth.frikke-schmidt@regionh.dk.ORCID http://orcid.org/0000-0003-4084-5027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the more than 90 identified genetic risk loci for late-onset Alzheimer's disease (AD) and related dementias, the apolipoprotein E (APOE) gene ɛ2/ɛ3/ɛ4 polymorphisms remain the longstanding benchmark for genetic disease risk with a consistently large effect across studies

Indexed as

Alzheimer DiseaseApolipoproteins EGenetic Predisposition to DiseaseGenome-Wide Association StudyApolipoprotein E4HumansPolymorphism, Single NucleotideQuantitative Trait LociApolipoprotein E4Apolipoproteins E

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.