Evidence map›Paper›PMID 42736314›Full record

ArticleNature communications2026

DUSP4 promotes anti-tumor CD8

Heng Li, Clara K T Koh, Tianshuai Zhang, Yi Lu, Chin Wen Png, Dong Van Hoang, Min Hui Oon, Choon Seng Chong, Kai Zhuang, Guanyu Yu and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Structure and function of the centromere and inner kinetochore.Nature reviews. Molecular cell biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Heng Li *NUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0003-4997-671X
Clara K T Koh *NUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0003-3467-9683
Tianshuai Zhang *Department of Colorectal Surgery, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China.
Yi LuNUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Chin Wen PngNUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Dong Van HoangNUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Min Hui OonNUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Choon Seng ChongDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Kai ZhuangSchool of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.
Guanyu YuDepartment of Colorectal Surgery, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China.ORCID http://orcid.org/0000-0001-5416-3559
Jie WanInstitute of Pediatric Infection, Immunity, and Critical Care Medicine, Shanghai Children's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0003-1539-3284
Ker-Kan TanDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Huanhuan LuoSchool of Basic Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China.ORCID http://orcid.org/0000-0003-2298-3418
Jun Siong LowDepartment of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Wei ZhangDepartment of Colorectal Surgery, Shanghai Changhai Hospital, Naval Medical University, Shanghai, China. weizhang2000cn@163.com.
Nicholas R J GascoigneNUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. ngascoigne@augusta.edu.ORCID http://orcid.org/0000-0001-9980-4225
Yongliang ZhangNUSMED Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. miczy@nus.edu.sg.ORCID http://orcid.org/0000-0002-4964-1285

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activation and function of CD8

Indexed as

CD8-Positive T-LymphocytesColorectal NeoplasmsDual-Specificity PhosphatasesMitogen-Activated Protein Kinase PhosphatasesProtein Tyrosine PhosphatasesAnimalsCell Line, TumorHumansMaleMiceMice, Inbred C57BLMice, KnockoutReceptors, Chimeric AntigenXenograft Model Antitumor AssaysDual-Specificity PhosphatasesDUSP4 protein, humanDusp4 protein, mouseMitogen-Activated Protein Kinase PhosphatasesProtein Tyrosine PhosphatasesReceptors, Chimeric Antigen

Identifiers

PMID42736314
PMCPMC13575141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.