ArticleNature communications2026
Odorant receptor coexpression and multi-expression in the dengue mosquito.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Revisiting the olfactory receptor rules.Nature reviews. Neuroscience · 2026Article
- Cyphers and cycles - A chemical basis of the differential attraction of mosquitoes to human odor.iScience · 2026Article
- Article
- A single-nucleus transcriptomic atlas of the adultbioRxiv : the preprint server for biology · 2025Article
- Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding.bioRxiv : the preprint server for biology · 2025Article
- An integrated anatomical, functional and evolutionary view of thebioRxiv : the preprint server for biology · 2025Article
- Gene expansion in the hawkmothiScience · 2024Article
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Abstract
Drosophila olfactory sensory neurons tend to express a single ligand-specific receptor, following a one-receptor-per-neuron rule expected to apply broadly across insects. Recent work challenges this view by showing that some neurons in the mosquito Aedes aegypti coexpress multiple receptors. However, the full extent and nature of coexpression in Ae. aegypti remains unclear. We sequenced the transcriptomes of 46,000 female antennal neurons to resolve all olfactory neuron subtypes and identify expressed receptors. Half of all subtypes coexpress multiple receptors. However, coexpression occurs almost exclusively among receptors from the same family; cross-family coexpression of odorant receptors with ionotropic receptors is rare. We also document a phenomenon called multi-expression, wherein one receptor is expressed in multiple neuron subtypes, often alongside distant paralogs. Drosophila provides rare examples of both coexpression and multi-expression, suggesting that Drosophila and Aedes are not fundamentally different, but instead located at different positions along a continuum likely to encompass diverse insects.
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