Evidence map›Paper›PMID 42736195›Full record

ArticlePoultry science2026

Individual and combined effects of vitamin E and lysolecithin supplementation on growth performance, serum biochemistry, antioxidant status, and gene expression in broiler chickens.

Abeer A Kirrella, Karima El-Naggar, Abeer G Zaki, Safaa E Abdo, Eman A Manaa, Asmaa F Khafaga, Ayham Abdulkader, Mahmoud Alagawany, Yahya Eid, Ibrahim A Elkhaiat

Abstract read
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abeer A KirrellaDepartment of Poultry Production, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, 333516, Egypt.
Karima El-NaggarDepartment of Nutrition and Veterinary Clinical Nutrition, Faculty of Veterinary Medicine, Alexandria University, Alexandria, 21944, Egypt.
Abeer G ZakiBiotechnology Department, Animal Health Research Institute (AHRI), Agricultural Research Centre (ARC), Giza, Egypt.
Safaa E AbdoGenetics and Genetic Engineering, Department of Animal Wealth Development, Faculty of Veterinary Medicine, Kafrelsheikh University, Post Box 33516, Egypt.
Eman A ManaaAnimal and Poultry Production and Breeding, Department of Animal Wealth Development, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh, 13736, Qalyubia, Egypt.
Asmaa F KhafagaDepartment of Pathology, College of Veterinary Medicine, King Faisal University, Al-Ahsa, 31982, Saudi Arabia. Electronic address: akhfajah@kfu.edu.sa.
Ayham AbdulkaderDepartment of Animal Production, Faculty of Veterinary Medicine, Idlib University, Syria. Electronic address: dr.ayhamabdulkader@gmail.com.
Mahmoud AlagawanyPoultry Department, Faculty of Agriculture, Zagazig University, Zagazig, 44511, Egypt.
Yahya EidDepartment of Poultry Production, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, 333516, Egypt.
Ibrahim A ElkhaiatDepartment of Poultry Production, Faculty of Agriculture, Kafrelsheikh University, Kafrelsheikh, 333516, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess their potential benefits in broiler production, the present experiment evaluated the effects of dietary supplementation with vitamin E (Vit E) and lysolecithin (LYSO) on growth performance, blood biochemical changes, intestinal and hepatic morphology, antioxidant status, meat quality, and gene expression. A total of 264 broiler chicks (Avian 48) were randomly assigned to six treatments for 35 days, each treatment containing four replicates of 11 birds. Treatments were arranged as follows: G1): control, G2): vitamin E (200 mg/kg diet), G3) 0.5 g LYSO/kg diet, G4) 1 g LYSO/kg diet, G5) 0.5 g LYSO + Vit E, and G6) 1 g LYSO+ Vit E. Broiler chickens supplemented with 1 g LYSO/kg diet + Vit E demonstrated the highest performance (higher body weight gain and improved feed conversion ratio) among groups (P < 0.05). Carcass and breast muscle weights were significantly increased, whereas abdominal fat was lowered in the supplemented groups (P < 0.05). In addition, dietary supplements improved phagocytic activity, intestinal and hepatic morphology, liver function-related enzymes (lower alanine aminotransferase-ALT, and aspartate aminotransferase-AST), serum lipid profile (lower low-density lipoproteins-LDL and triglycerides, along with higher high-density lipoproteins-HDL levels), and antioxidant enzyme activities (superoxide dismutase-SOD, glutathione peroxidase-GPx, and catalase-CAT), while lowering malondialdehyde (MDA) levels (P < 0.05) in birds fed the combination (1 g LYSO/kg diet + Vit E). The combination also stimulated significant upregulation of growth hormone receptor (GHR) and insulin-like growth factor (IGF-1), and immune response (Interleukins-, IL-10 and IL-1β) related genes (P < 0.05), while the lipogenic gene, ACC, was downregulated (P < 0.05). Dietary supplementation of feed additives increased meat-water holding capacity, tenderness, and color (P < 0.05), with no effect on meat pH. In conclusion, the combined supplementation of LYSO (1 g/kg diet) and vitamin E improved broiler growth, serum lipid profile and liver function, tissue morphology, immune function, antioxidant status, and meat quality, highlighting its potential as an effective nutritional approach in broiler production.

Indexed as

AntioxidantsBroilerGrowthMeat qualityVitamin E and lysolecithin

Identifiers

PMID42736195
PMCPMC13594812

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.