Evidence map›Paper›PMID 42735672›Full record

ArticleUltrasonics sonochemistry2026

Ultrasound-assisted green hydrophobic deep eutectic solvents extraction of capsanthin from red peppers: optimization, kinetics, stability, and insights into extraction mechanisms.

Zhongxu Li, Caihong Cheng, Jialin Xue, Qingyang Sun, Lixiang Huai, Yuting Xiao, Xianjin Zhou, Yaya Yao, Ruiguo Cui, Lijun Song

Abstract read
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In one paragraph

Article in Ultrasonics sonochemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Zhongxu LiCollege of Food Science and Technology, Hebei Normal University of Science & Technology, Qinhuangdao 066612, China.
Caihong ChengHebei Key Laboratory of Natural Products Activity Components and Function, Hebei Normal University of Science & Technology, Qinhuangdao 066004, China.
Jialin XueCollege of Food Science and Technology, Hebei Normal University of Science & Technology, Qinhuangdao 066612, China.
Qingyang SunCollege of Food Science and Technology, Hebei Normal University of Science & Technology, Qinhuangdao 066612, China.
Lixiang HuaiCollege of Food Science and Technology, Hebei Normal University of Science & Technology, Qinhuangdao 066612, China.
Yuting XiaoCollege of Food Science and Technology, Hebei Normal University of Science & Technology, Qinhuangdao 066612, China.
Xianjin ZhouBazhoujiamu Agroscience Co., Ltd., Korla, Xinjiang, China.
Yaya YaoCollege of Food Science and Technology, Hebei Normal University of Science & Technology, Qinhuangdao 066612, China.
Ruiguo CuiCollege of Food Science and Technology, Hebei Normal University of Science & Technology, Qinhuangdao 066612, China; Chestnut Research Center of Hebei Normal University of Science & Technology, Qinhuangdao 066604, Hebei, China.
Lijun SongHebei Key Laboratory of Natural Products Activity Components and Function, Hebei Normal University of Science & Technology, Qinhuangdao 066004, China; Chestnut Research Center of Hebei Normal University of Science & Technology, Qinhuangdao 066604, Hebei, China. Electronic address: slj176@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capsanthin is a widely used natural pigment, but its extraction with traditional solvents suffers from low efficiency and environmental pollution. To address these issues, this study employed ultrasonic-assisted hydrophobic deep eutectic solvent (HDES) to extract capsanthin. The thymol: menthol (molar ratio 1:2) (HDES-3) was selected as the optimum solvent. The extraction process of capsanthin conformed to Fick's second law. FTIR and SEM analyses confirmed that hydrogen bond interactions between HDES components led to its formation. HDES-3 had the most obvious destructive effect on the raw material structure and showed a stronger extraction ability. Density functional theory (DFT) and molecular dynamics (MD) simulations were employed to further explore the interaction between HDES-3 and capsanthin. The main interactions between capsanthin and HDESs were van der Waals forces and hydrogen bonds with van der Waals forces playing the dominant role. Meanwhile, the more stable hydrogen bond between HDES-3 and capsanthin enhances the stability of capsanthin. This study provides an efficient and green alternative to the use of traditional solvents in the extraction of capsanthin.

Indexed as

CapsicumChemical FractionationDeep Eutectic SolventsGreen Chemistry TechnologyHydrophobic and Hydrophilic InteractionsUltrasonic WavesXanthophyllsHydrogen BondingKineticsMolecular Dynamics SimulationSolventscapsanthinDeep Eutectic SolventsSolventsXanthophyllsCapsanthinDensity functional theoryHydrophobic deep eutectic solventMolecular dynamics simulationsRed peppers

Identifiers

PMID42735672
PMCPMC13594946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.