Evidence map›Paper›PMID 42735433›Full record

Observational studyJMIR mHealth and uHealth2026

Daily Reminders Increase Adherence to an Electronic Headache Diary (DMKG-App): Retrospective Longitudinal Cohort Study.

Ruth Ruscheweyh, Lars Neeb, Bianca Raffaelli, Torsten Kraya, Tobias Freilinger, Thomas Dresler, Gudrun Gossrau, Tim Patrick Jürgens, Victoria Ruschil, Jörg Scheidt and 1 more

Abstract readObservational Study
In one paragraph

Observational study in JMIR mHealth and uHealth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ruth RuscheweyhDepartment of Neurology, LMU University Hospital, LMU Munich, Marchioninistr. 15, Munich, 81377, Germany, 49 89-4400-52455.ORCID http://orcid.org/0000-0001-9510-7158
Lars NeebDepartment of Neurology, Brandenburg Medical School, Theodor Fontane, University Hospital Brandenburg/Havel, Brandenburg/Havel, Germany.ORCID http://orcid.org/0000-0002-1940-6399
Bianca RaffaelliDepartment of Neurology, Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.ORCID http://orcid.org/0000-0001-9758-1494
Torsten KrayaDepartment of Neurology, Hospital Sankt Georg Leipzig gGmbH, Leipzig, Germany.ORCID http://orcid.org/0000-0002-6060-3810
Tobias FreilingerDepartment of Neurology, Klinikum Passau, Passau, Germany.ORCID http://orcid.org/0009-0007-8071-1521
Thomas DreslerDepartment of Psychiatry and Psychotherapy, Tuebingen Center for Mental Health, University Hospital Tuebingen, Tuebingen, Germany.ORCID http://orcid.org/0000-0003-2084-1950
Gudrun GossrauInterdisciplinary Pain Center, University Hospital and Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-0995-5482
Tim Patrick JürgensDepartment of Neurology, Headache Center North-East, University Medical Center Rostock, Rostock, Germany.ORCID http://orcid.org/0000-0002-4394-7136
Victoria RuschilCenter for rare diseases, University Hospital Tuebingen, Tuebingen, Germany.ORCID http://orcid.org/0000-0002-1442-9997
Jörg ScheidtInstitute for Information Systems, University of Applied Sciences Hof, Hof, Germany.ORCID http://orcid.org/0000-0001-9742-6080
Yannic SiebenhaarInstitute for Information Systems, University of Applied Sciences Hof, Hof, Germany.ORCID http://orcid.org/0009-0006-4351-2331

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The use of electronic headache diaries via smartphone apps has several advantages over paper and pencil diaries. Still, adherence is not always satisfactory. One potential strategy to improve adherence is the implementation of daily reminders, but their effect remains uncertain. Objective: The DMKG-App (the headache diary app of the German Migraine and Headache Society, DMKG) sends daily reminders to encourage user adherence. Due to a technical problem, reminders failed for a 14-day period in early 2023. This provided a unique opportunity to evaluate the effect of daily reminders on adherence to the headache diary in the form of a retrospective longitudinal observational cohort study. Methods: The failure period was compared to 14-day prefailure and postfailure periods and to corresponding periods of the previous year. We evaluated effects on the number of daily entries, delay to make the daily entry, and attrition rate, using ANOVA and logistic regression (α<.05). The effect of age, gender, headache frequency, and previous adherence was investigated using interaction analysis. Results: The DMKG-App had 4236 active users before reminders failed (females 81.6%, 95% CI 80.5-82.8), age 39.8 (95% CI 39.4-40.2) years. During the failure period, the number of daily entries fell by 11.0% (95% CI 9.2-12.8). More specifically, entries per 14-day period significantly declined from 10.2 (95% CI 10.1-10.3) prefailure to 9.1 (95% CI 9.0-9.2) during the failure period, followed by a rise to 10.2 (95% CI 10.1-10.3) during the postfailure period ( Conclusions: This is the first study investigating the effect of daily reminders in a digital headache diary app. Results suggest that reminders are an effective means to improve adherence. Males, persons with low headache frequencies, and those with high adherence during the presence of reminders seem to benefit most. These results are important additions to our knowledge on compliance with digital health apps.

Indexed as

Diaries as TopicHeadacheMobile ApplicationsPatient ComplianceReminder SystemsAdultCohort StudiesFemaleGermanyHumansLogistic ModelsLongitudinal StudiesMaleMiddle AgedRetrospective Studiesadherenceattrition rateelectronic headache diaryentry delayheadache

Identifiers

PMID42735433
PMCPMC13574331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.