Evidence map›Paper›PMID 42735292›Full record

Observational studyInternational journal of urology : official journal of the Japanese Urological Association2026

Sexual Dysfunction and Lower Urinary Tract Dysfunction in Adults With Spina Bifida.

Daisuke Gotoh, Akira Tachibana, Yuki Oda, Mitsuru Tomizawa, Kenta Onishi, Shunta Hori, Yosuke Morizawa, Yasushi Nakai, Makito Miyake

Abstract readObservational Study
In one paragraph

Observational study in International journal of urology : official journal of the Japanese Urological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daisuke GotohDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0002-6056-3820
Akira TachibanaDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0003-1848-4237
Yuki OdaDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0003-3909-1133
Mitsuru TomizawaDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0002-9065-7828
Kenta OnishiDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0003-1767-9905
Shunta HoriDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0001-9514-9964
Yosuke MorizawaDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0001-7142-5901
Yasushi NakaiDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0002-7579-0372
Makito MiyakeDepartment of Urology, Nara Medical University, Kashihara-shi, Nara, Japan.ORCID https://orcid.org/0000-0001-9503-7356

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate sexual function and lower urinary tract dysfunction in adults with spina bifida (SB) compared with healthy controls and their impact on quality of life (QOL).

methodsIn this prospective observational study, 30 adults with SB (21 women, 9 men) and 28 healthy volunteers (17 women, 11 men) were enrolled (September 2023-December 2024). Sexual and urinary function were assessed with the FSFI, SHIM, IPSS, Overactive Bladder Symptom Score, ICIQ-SF, and King's Health Questionnaire. Group differences were analyzed with Mann-Whitney U or chi-square tests with Benjamini-Hochberg correction; effect sizes were reported as rank-biserial r or Cramér's.

resultsPatients with SB had significantly poorer sexual and lower urinary tract function than controls. In women, sexual desire was relatively preserved (q = 0.21, r = 0.20), whereas arousal, lubrication, orgasm, and satisfaction were markedly reduced (all q ≤ 0.003, r = 0.51-0.79). In men, erectile function was severely impaired (SHIM total 3.0 vs. 21.0; q = 0.0006, r = 0.81). IPSS and ICIQ-SF totals were higher in the SB group in both sexes (all q ≤ 0.0004, r ≥ 0.79). IPSS-QOL correlated with ICIQ-SF in both women (Spearman r = 0.57, p = 0.009) and men (r = 0.80, p = 0.011).

conclusionsAdults with SB had substantial sexual and lower urinary tract dysfunction. Sexual desire was relatively preserved in women, whereas urinary incontinence was associated with poorer QOL.

Indexed as

Lower Urinary Tract SymptomsSexual Dysfunction, PhysiologicalSpinal DysraphismAdultCase-Control StudiesFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeYoung Adultneurogenic lower urinary tract dysfunctionprospective observational studyquality of lifesexual dysfunctionspina bifida

Identifiers

PMID42735292
PMCPMC13574301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.