Evidence map›Paper›PMID 42734797›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2027

Plaque Reduction Neutralization Test Against Chikungunya Virus Using Liver Homogenate.

Thais Alkifeles Costa, Betânia Paiva Drumond

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thais Alkifeles CostaLaboratório de Vírus, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 31270-901, Brazil.
Betânia Paiva DrumondLaboratório de Vírus, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, 31270-901, Brazil. betaniadrumond@gmail.com.

Funding

Extended follow-up of randomized participants in the INSIGHT START trialU01AI136780 · NIAID · UNIVERSITY OF MINNESOTA · PI GRUND, BIRGIT, REILLY, CAVAN S. · 2019 to 2024
$18.0M
Emerging Infectious Diseases Research Centers Coordination Center (EIDRC CC)U01AI151378 · NIAID · RESEARCH TRIANGLE INSTITUTE · PI Gregory D Sempowski · 2020 to 2026
$14.7M
Coordinating Research on Emerging Arboviral Threats Encompassing the Neotropics II (CREATE-NEO II)U01AI151807 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Kathryn Alyce Hanley, MAURICIO Lacerda NOGUEIRA · 2020 to 2026
$9.8M
NIAID NIH HHS U01 AI136780NIAID NIH HHS U01 AI151378NIAID NIH HHS U01 AI151807
6 · The paper itself

Abstract

We adapted the plaque reduction neutralization test (PRNT) to detect chikungunya virus (CHIKV) neutralizing antibodies in liver homogenates instead of serum. This approach enables serological investigation using tissues collected from animal carcasses as nonhuman primate ones, during arbovirus surveillance, expanding opportunities for CHIKV monitoring and strengthening epidemiological surveillance efforts.

Indexed as

Antibodies, NeutralizingAntibodies, ViralChikungunya FeverChikungunya virusLiverNeutralization TestsViral Plaque AssayAnimalsAntibodies, NeutralizingAntibodies, ViralAdapted viral neutralization testArbovirus surveillanceChikungunya virusNeutralizing antibodiesPRNTSerological surveillanceViral neutralization

Identifiers

PMID42734797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.