Evidence map›Paper›PMID 42734756›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2027

Genomic Profiling of Chromatin State Using CUT&Tag.

Fanju W Meng, Duy K Nguyen, Patrick J Murphy

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fanju W MengDepartment of Biological Sciences, Advanced Environmental Research Institute, University of North Texas, 1155 Union Circle #305220, Denton, TX, 76203, USA.
Duy K NguyenDepartment of Pathology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, 14642, USA.
Patrick J MurphyDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14850, USA. pjm249@cornell.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in chromatin state, mediated through histone modifications and the incorporation of histone variants, are fundamental to establishing transcriptional networks and cell identity. Recent advances in low-input epigenome profiling methods, such as CUT&Tag and CUT&RUN, have enabled the study of chromatin states from very limited starting materials. In this chapter, we describe procedures for generating CUT&Tag libraries to profile histone modifications and histone variants in early-developing zebrafish embryos.

Indexed as

ChromatinEpigenomicsGenomicsAnimalsEpigenesis, GeneticHistone CodeHistonesZebrafishChromatinHistonesChromatinCUT&TagEmbryogenesisEpigeneticsEpigenomeHistone modificationsHistone variantsZebrafish

Identifiers

PMID42734756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.