Evidence map›Paper›PMID 42734460›Full record

ReviewMedical gas research2027

Molecular hydrogen: a potential guardian against environmental radiation damage.

Yusuke Ichikawa, Bunpei Sato, Yoshiyasu Takefuji, Fumitake Satoh

Abstract readReview
In one paragraph

Review in Medical gas research, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yusuke IchikawaResearch and Development Department, MiZ Company Limited, Kanagawa, Japan.ORCID 0000-0002-2526-4681
Bunpei SatoResearch and Development Department, MiZ Company Limited, Kanagawa, Japan.
Yoshiyasu TakefujiFaculty of Data Science, Musashino University, Tokyo, Japan.
Fumitake SatohResearch and Development Department, MiZ Company Limited, Kanagawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular hydrogen is known to selectively convert hydroxyl radicals into harmless water and thereby mitigating oxidative stress. Due to hydrogen molecules have masses comparable to protons and neutrons, can also decelerate neutrons and protons present in environmental radiation, thus exerting a physical shielding effect. Through this dual action, chemical radical scavenging and physical radiation shielding, hydrogen may protect cellular integrity and potentially promote biological longevity. In contrast, hydrogen can intervene at the stage of preventing biomolecular damage induced by environmental radiation and provide comprehensive protection at the tissue and cellular levels, uniquely minimizing radiation-induced damage. This review systematically summarizes existing knowledge regarding the antioxidant and radioprotective effects of hydrogen, discusses its role in mitigating oxidative stress and protecting cells from environmental radiation, and proposes a novel hypothesis that hydrogen has universally protected from radiation-induced damage, highlighting its potential for promoting biological longevity.

Indexed as

HydrogenRadiation-Protective AgentsAnimalsAntioxidantsHumansOxidative StressAntioxidantsHydrogenRadiation-Protective Agentsagingenvironmental radiationhydrogenhydroxyl radicaloxidative damageoxidative stressradiation resistancesenescent cells

Identifiers

PMID42734460
PMCPMC13667370

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.