Evidence map›Paper›PMID 42734456›Full record

ReviewMedical gas research2027

Hydrogen sulfide-releasing hydrogels: a new perspective on clinical translation.

Yue Xu, Zongchi Liu, Zongpu Xu, Yu Zhu

Abstract readReview
In one paragraph

Review in Medical gas research, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yue XuDepartment of Neurosurgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.
Zongchi LiuDepartment of Neurosurgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.
Zongpu XuInstitute of Applied Bioresources, College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang Province, China.ORCID 0000-0001-6868-2712
Yu ZhuDepartment of Neurosurgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, China.ORCID 0000-0001-8360-4368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen sulfide (H2S), an endogenous gaseous signaling molecule, plays crucial roles in physiological regulation. However, efficient delivery and controlled release of H2S remain major challenges for clinical application. Hydrogels, with the unique three-dimensional network structure, provide a versatile platform for H2S loading and controlled release, offering a promising strategy to address these limitations. This article reviews the fabrication strategies of H2S-releasing hydrogels, including H2S donors, hydrogel properties, and incorporation strategies. In addition, biomedical applications of H2S-releasing hydrogels, including neurological therapy, cardiovascular therapy, regulation of vascular tone and angiogenesis, bone metabolism, wound healing, and others, are discussed. By integrating current advances, the article aims to provide new perspectives for the further development and clinical translation of H2S-releasing hydrogels.

Indexed as

HydrogelsHydrogen SulfideTranslational Research, BiomedicalAnimalsHumansHydrogelsHydrogen Sulfideangiogenesisbiomedicalcardiovascularhydrogelhydrogen sulfidemetabolismneuroprotectionvasodilationwound healing

Identifiers

PMID42734456
PMCPMC13667861

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.