Evidence map›Paper›PMID 42734113›Full record

ArticleJournal of comparative effectiveness research2026

A trial emulation study indirectly comparing tafamidis and acoramidis in transthyretin amyloid cardiomyopathy: the ReplicATTR study.

Philippe Debonnaire, Peter-Paul Zwetsloot, Roman Pfister, Pau Llàcer, Alberto Cipriani, Paolo Milani, Diana Bonderman, Christoph Ohlmeier, Thomas Evers, Richard Wyss and 6 more

Abstract readComparative Study
In one paragraph

Article in Journal of comparative effectiveness research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Philippe DebonnaireDepartment of Cardiology, AZ Sint-Jan Brugge, Bruges, Belgium.ORCID 0000-0003-1196-3016
Peter-Paul ZwetslootCardiovascular Institute, Thoraxcenter, Department of Cardiology, Erasmus Medical Centre, Rotterdam, The Netherlands.ORCID 0000-0002-2634-4667
Roman PfisterFaculty of Medicine & University Hospital Cologne, Clinic III for Internal Medicine, University of Cologne, Cologne, Germany.ORCID 0000-0002-4358-5008
Pau LlàcerInternal Medicine Department, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.ORCID 0000-0002-0988-0599
Alberto CiprianiDepartment of Cardiothoracic & Vascular Sciences & Public Health, Padova University Hospital, Padova, Italy.ORCID 0000-0001-7842-6202
Paolo MilaniDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.ORCID 0000-0002-2268-9422
Diana BondermanDepartment of Cardiology, Clinic Favoriten, Wien, Austria.ORCID 0000-0002-6885-5924
Christoph OhlmeierBayer AG, Berlin, Germany.ORCID 0000-0002-2868-5211
Thomas EversBayer AG, Wuppertal, Germany.ORCID 0000-0002-9417-6773
Richard WyssDivision of Pharmacoepidemiology & Pharmacoeconomics, Department of Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA 02120, USA.ORCID 0009-0007-6832-5900
Elisabetta PatornoDivision of Pharmacoepidemiology & Pharmacoeconomics, Department of Medicine, Brigham & Women's Hospital & Harvard Medical School, Boston, MA 02120, USA.ORCID 0000-0002-8809-9898
Riddhi DoshiIQVIA Ltd., London, UK.ORCID 0000-0002-1439-1511
Julien BeiselIQVIA Ltd., London, UK.
Craig I ColemanUniversity of Connecticut School of Pharmacy, Storrs, CT 06269, USA.ORCID 0000-0003-4868-7158
Carlos AguiarSanta Cruz Hospital, Carnaxide, Portugal.ORCID 0000-0002-5970-6353
Tomas Ripoll-VeraSon Llàtzer University Hospital & IdISBa, Palma, Balearic Islands, Spain.ORCID 0000-0001-9222-325X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amyloid Neuropathies, FamilialBenzoxazolesCardiomyopathiesAgedBenzoic AcidFemaleHumansMalePyrazolesacoramidisBenzoic AcidBenzoxazolesPyrazolestafamidisacoramidisall-cause mortalityATTR-CMcomparative effectiveness researchtafamidistarget trial emulationtransthyretin amyloid cardiomyopathytransthyretin stabilizer

Identifiers

PMID42734113
PMCPMC13648057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.