Evidence map›Paper›PMID 42733847›Full record

ArticleInternational journal of women's health2026

Lymphadenectomy During Interval Debulking Surgery in Advanced Epithelial Ovarian Cancer: A Multicenter Real-World Study.

Xingyu Liu, Yiyang Shen, Yingjun Zhao, Qinglei Gao, Ting Hu

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Article in International journal of women's health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Xingyu Liu *Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Yiyang Shen *Department of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Yingjun ZhaoDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Qinglei GaoDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.ORCID 0000-0002-9448-3423
Ting HuDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetrics and Gynecology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.ORCID 0000-0002-9693-4697

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the controversial impact of lymphadenectomy on prognosis and postoperative complications in patients with advanced epithelial ovarian cancer (AEOC) receiving neoadjuvant chemotherapy followed by interval debulking surgery (IDS). Methods: This retrospective real-world study analyzed 1068 patients with AEOC undergoing IDS at seven tertiary centers in China between 2006 and 2021. Endpoints included progression-free survival (PFS), overall survival (OS), and postoperative complications. Propensity score matching (PSM) and overlapping weight (OW) analyses were employed to minimize selection bias. Results: Of the cohort, 528 patients (49.4%) underwent lymphadenectomy. After adjustment, 960 patients were matched in the propensity score matching cohort (480 per group), and 1068 patients were included in the overlapping weight cohort. Lymphadenectomy was consistently associated with improved PFS in the unadjusted (HR, 0.77; 95% CI, 0.67-0.90; Conclusion: In this multicenter retrospective cohort study, lymphadenectomy during IDS was associated with improved PFS but not OS after adjustment. No increased risk of postoperative complications was observed. Given the retrospective design, prospective studies are needed to validate these findings and clarify the role of lymphadenectomy.

Indexed as

advanced epithelial ovarian cancerinterval debulking surgerylymphadenectomypostoperative complicationprognosis

Identifiers

PMID42733847
PMCPMC13571674

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.