Evidence map›Paper›PMID 42733785›Full record

ReviewBioactive materials2027

Harnessing gasotransmitters for orthopaedic infection therapy: Mechanisms and advanced delivery platforms.

Jun-Yi Zhang, Yi-Qi Yang, Zhi-Xiong Zhang, Jia-Le Jin, Zhi-Yuan Luo, Dong-Yu Wang, Cheng-Xin Ruan, Tian-Zheng Dai, Yi-Lun Huang, Jie Xu and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Bioactive materials, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jun-Yi ZhangDepartment of Orthopaedics, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou City, Zhejiang Province, 313000, China.
Yi-Qi YangDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Zhi-Xiong ZhangDepartment of Orthopaedics, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou City, Zhejiang Province, 313000, China.
Jia-Le JinDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Zhi-Yuan LuoDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Dong-Yu WangDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Cheng-Xin RuanDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Tian-Zheng DaiSchool of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang, 310018, China.
Yi-Lun HuangDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Jie XuDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.
Jia-Wei ShiHuzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, China.
Jian-You LiDepartment of Orthopaedics, Huzhou Central Hospital, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, Huzhou City, Zhejiang Province, 313000, China.
Peng-Fei LeiDepartment of Orthopaedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthopaedic infections are increasingly prevalent in the aging population, posing a significant clinical and economic burden. Despite progress in antimicrobial therapies, challenges such as antibiotic resistance and superbug emergence persist. Gas therapy has emerged as a promising strategy for managing orthopaedic infections. Classical gasotransmitters-including nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H

Indexed as

GasotransmittersGas therapyOrthopaedic infectionsSmart delivery systemsTissue regeneration

Identifiers

PMID42733785
PMCPMC13571535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.