Evidence map›Paper›PMID 42733774›Full record

ArticleJournal of the American College of Emergency Physicians open2026

Evaluating the Whole Blood Survival Advantage: How Citrate and Calcium Levels Drive Mortality in a Translational Swine Model of Polytrauma.

Jason M Rall, Craig D Nowadly, Jae-Hyek Choi, Heang Sundermann, Kaysie Sutton, Allyson A Arana, Dena Norouzi, R Madelaine Paredes, Joseph K Maddry

Abstract read
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In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jason M RallOffice of the Chief Scientist, Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, JBSA-Lackland, Texas, USA.
Craig D NowadlyOffice of the Chief Scientist, Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, JBSA-Lackland, Texas, USA.
Jae-Hyek ChoiOffice of the Chief Scientist, Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, JBSA-Lackland, Texas, USA.
Heang SundermannOffice of the Chief Scientist, Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, JBSA-Lackland, Texas, USA.
Kaysie SuttonOffice of the Chief Scientist, Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, JBSA-Lackland, Texas, USA.
Allyson A AranaEn Route Care Research Center, JBSA Fort Sam Houston, Texas, USA.
Dena NorouziOffice of the Chief Scientist, Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, JBSA-Lackland, Texas, USA.
R Madelaine ParedesOffice of the Chief Scientist, Wilford Hall Ambulatory Surgical Center, 59th Medical Wing, JBSA-Lackland, Texas, USA.
Joseph K MaddryDepartment of Emergency Medicine, Brooke Army Medical Center, Joint Base San Antonio - Fort Sam Houston, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Whole blood (WB) is increasingly used for trauma resuscitation, but clinical comparisons with component therapy (COMP) have reported mixed survival results, and physiologic contributors to any differences remain incompletely defined. We evaluated the association between excess citrate exposure, calcium (Ca Methods: In a randomized swine ( Results: Baseline values were similar across groups. Survival was 3 of 8 animals in COMP/-Ca and 8 of 8 animals in each other group (log-rank Conclusions: In this polytrauma model, simulated COMP with excess citrate and without Ca

Indexed as

calciumcitratehemorrhagehypocalcemiaresuscitationtrauma

Identifiers

PMID42733774
PMCPMC13571567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.