Evidence map›Paper›PMID 42733654›Full record

ReviewThe Japanese dental science review2026

Is infraocclusion always caused by ankylosis? Current perspectives on primary molar ankylosis: A systematic review.

Masatoshi Otsugu, Hamada Masakazu, Fumikazu Tojo, Kazuhiko Nakano

Abstract readReview
In one paragraph

Review in The Japanese dental science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Masatoshi OtsuguDepartment of Pediatric Dentistry, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.
Hamada MasakazuDepartment of Oral & Maxillofacial Oncology and Surgery, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.
Fumikazu TojoDepartment of Pediatric Dentistry, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.
Kazuhiko NakanoDepartment of Pediatric Dentistry, Graduate School of Dentistry, The University of Osaka, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ankylosed primary molars are relatively common during the mixed dentition period; however, ankylosis does not always coincide with infraocclusion. This systematic review assessed the clinical evidence regarding ankylosis of primary molars, including its etiology, diagnosis, and management, and discussed whether infraocclusion is primarily caused by ankylosis or instead reflects a broader disturbance of tooth eruption. A literature search was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines across three databases (PubMed, Scopus, and Web of Science) on 25 April 2025 and updated on 3 July 2026. The risk of bias and methodological quality of the included studies were assessed using the Joanna Briggs Institute critical appraisal tools. Fourteen studies met the inclusion criteria. The person-level prevalence of infraoccluded primary molars, used as a surrogate for ankylosis, ranged from 1.3% to 24.8%. Histopathological and clinical studies indicated that not all infraoccluded primary molars exhibited evidence of ankylosis. Treatment strategies varied according to the severity of infraocclusion and the presence or absence of permanent successors. The available evidence remains limited and insufficient to determine the temporal and causal relationship between ankylosis and infraocclusion. Further epidemiological, histopathological, and treatment-related studies are needed.

Indexed as

AnkylosisDeciduous molarInfraocclusionPrimary molarSystematic review

Identifiers

PMID42733654
PMCPMC13571401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.