Evidence map›Paper›PMID 42733571›Full record

ArticleResuscitation plus2026

Temporal trends in chest compression quality during a metronome-guided CPR simulation: a secondary analysis of the RITMICO study.

Giuliana Monachino, Valentina Guerini Giusteri, Ruggero Cresta, Alessia Currao, Enrico Baldi, Simone Savastano, Andrea Cortegiani, Mariachiara Ippolito, Alessandra Gargano, Camilla Metelmann and 11 more

Abstract read
In one paragraph

Article in Resuscitation plus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Giuliana MonachinoUniversity of Applied Sciences and Arts of Southern Switzerland (SUPSI), Department of Innovative Technologies (DTI) - MeDiTech Institute, Lugano, Switzerland.
Valentina Guerini GiusteriCardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Ruggero CrestaTicino Cuore Foundation, Lugano, Switzerland.
Alessia CurraoDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Enrico BaldiDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Simone SavastanoDivision of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.
Andrea CortegianiDepartment of Anesthesia, Analgesia, Intensive Care and Emergency, University Hospital Policlinico Paolo Giaccone, Palermo, Italy.
Mariachiara IppolitoDepartment of Anesthesia, Analgesia, Intensive Care and Emergency, University Hospital Policlinico Paolo Giaccone, Palermo, Italy.
Alessandra GarganoDepartment of Anesthesia, Analgesia, Intensive Care and Emergency, University Hospital Policlinico Paolo Giaccone, Palermo, Italy.
Camilla MetelmannDepartment of Anaesthesia, Intensive Care Medicine, Emergency Medicine and Pain Medicine, University Medicine Greifswald, Germany.
Bibiana MetelmannDepartment of Anaesthesia, Intensive Care Medicine, Emergency Medicine and Pain Medicine, University Medicine Greifswald, Germany.
Carlos Roman HölzingDepartment of Anaesthesia, Intensive Care Medicine, Emergency Medicine and Pain Medicine, University Medicine Greifswald, Germany.
Julian GanterDepartment of Anaesthesiology and Critical Care, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.
Michael MuellerDepartment of Anaesthesiology, Intensive Care and Emergency Medicine, St. Josefs Hospital, Freiburg, Germany.
Claudio BenvenutiTicino Cuore Foundation, Lugano, Switzerland.
Stefania TomolaCentro di Simulazione (CeSi), Centro Professionale Sociosanitario Medico-Tecnico di Lugano, Switzerland.
Pierangelo PinettiCentro di Simulazione (CeSi), Centro Professionale Sociosanitario Medico-Tecnico di Lugano, Switzerland.
Pier Luigi IngrassiaCentro di Simulazione (CeSi), Centro Professionale Sociosanitario Medico-Tecnico di Lugano, Switzerland.
Giulio ConteCardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.
Francesca D FaraciUniversity of Applied Sciences and Arts of Southern Switzerland (SUPSI), Department of Innovative Technologies (DTI) - MeDiTech Institute, Lugano, Switzerland.
Maria Luce CaputoCardiocentro Ticino Institute, Ente Ospedaliero Cantonale, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: High-quality cardiopulmonary resuscitation (CPR) is essential for improving outcomes after out-of-hospital cardiac arrest. The RITMICO study evaluated a newly developed double-click metronome, providing separate auditory cues for the compression and release phases, compared with a standard metronome. This secondary analysis investigated temporal changes in chest compression (CC) quality during prolonged manikin-based CPR simulations and explored factors associated with these trajectories. Methods: 477 volunteers (54% male; mean age 34 ± 12 years) were included in the analysis. Compression depth, compression rate, and chest compression release velocity (CCRV) were recorded using an automated external defibrillator with CC quality analysis technology. Simulations were divided into 21 consecutive 5-s intervals, and median values for each metric were analyzed using linear mixed-effects models with subject-specific random effects. Results: Compression depth and CCRV progressively declined over time, indicating early deterioration in CPR quality during prolonged compressions. Compared with the standard metronome, the double-click metronome produced consistently higher values for all CPR quality metrics throughout the simulation (all Conclusions: CPR quality deteriorated early during prolonged simulated chest compressions, particularly with respect to chest recoil. The use of a double-click metronome was associated with better preservation of CPR quality over time and a later deterioration in CCRV. These findings support a potential role for the double-click metronome in maintaining CPR quality during prolonged resuscitation, although confirmation in real-world clinical settings is needed.

Indexed as

CPR qualityOut-of-hospital cardiac arrestPerformanceSimulation training

Identifiers

PMID42733571
PMCPMC13571548

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.