Evidence map›Paper›PMID 42733508›Full record

ArticleCureus2026

Silent but Serious: Astrocytoma in a Seven-Month-Old Infant With Atypical Presentation.

Priscilla Chong, Kulsoom Bilal, Imran Ahmed, Haji Sheeraz Khan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Priscilla ChongPaediatric Department, Hull University Teaching Hospitals NHS Trust, Kingston Upon Hull, GBR.
Kulsoom BilalPaediatric Department, Hull University Teaching Hospitals NHS Trust, Kingston Upon Hull, GBR.
Imran AhmedPaediatric Department, Hull University Teaching Hospitals NHS Trust, Kingston Upon Hull, GBR.
Haji Sheeraz KhanPaediatric Department, Hull University Teaching Hospitals NHS Trust, Kingston Upon Hull, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pilocytic astrocytoma (PA) is a common paediatric brain tumour that usually presents with neurological or visual symptoms linked to its location. This report describes a seven-month-old boy with an unusual presentation marked by poor feeding, progressive weight loss, and recurrent vomiting over three months, without early neurological signs. Extensive initial assessments, including feeding evaluations, multidisciplinary reviews, and pharmacological trials, did not reveal a cause. Ultimately, neuroimaging identified a large suprasellar mass with leptomeningeal deposits. Following lumbar puncture, histopathological examination of the biopsy specimen, and molecular testing, the diagnosis of PA was confirmed. Treatment was subsequently initiated with carboplatin and vincristine. Unlike typical PA cases, which often involve headaches, visual problems, or motor deficits, this case underscores that systemic, nonspecific symptoms can signal central nervous system disease. The report highlights the importance of considering neuroimaging in infants with persistent vomiting and failure to thrive to enable earlier diagnosis and potentially improve outcomes in atypical PA presentations.

Indexed as

brain tumourfailure-to-thrivepaediatrics neuro-oncologypersistent vomitingpilocytic astrocytoma (pa)

Identifiers

PMID42733508
PMCPMC13571106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.