Evidence map›Paper›PMID 42733446›Full record

ArticleBiological psychiatry global open science2026

Changing Patterns of Recent Substance Use in Emerging Adulthood and Their Associations With Cognitive Functions and Mental Health.

Lukas Eggenberger, Clarissa Janousch, Lydia Johnson-Ferguson, Markus R Baumgartner, Tina M Binz, Denis Ribeaud, Manuel Eisner, Lilly Shanahan, Boris B Quednow

Abstract read
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In one paragraph

Article in Biological psychiatry global open science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lukas EggenbergerExperimental Pharmacopsychology and Psychological Addiction Research, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.
Clarissa JanouschExperimental Pharmacopsychology and Psychological Addiction Research, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.
Lydia Johnson-FergusonExperimental Pharmacopsychology and Psychological Addiction Research, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.
Markus R BaumgartnerCenter for Forensic Hair Analytics, Zurich Institute of Legal Medicine, University of Zurich, Zurich, Switzerland.
Tina M BinzCenter for Forensic Hair Analytics, Zurich Institute of Legal Medicine, University of Zurich, Zurich, Switzerland.
Denis RibeaudJacobs Center for Productive Youth Development, University of Zurich, Zurich, Switzerland.
Manuel EisnerJacobs Center for Productive Youth Development, University of Zurich, Zurich, Switzerland.
Lilly ShanahanJacobs Center for Productive Youth Development, University of Zurich, Zurich, Switzerland.
Boris B QuednowExperimental Pharmacopsychology and Psychological Addiction Research, Department of Adult Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Emerging adulthood is a developmental period marked by heightened risk for illicit substance use, potentially influencing neurocognitive development and mental health. However, longitudinal and objective data on changing patterns of substance use and their associated neuropsychiatric outcomes remain scarce. Longitudinal monitoring of substance use could inform targeted prevention strategies during this sensitive developmental period. Methods: This Swiss longitudinal cohort study included 731 emerging adults. Hair concentrations of >100 psychoactive substances and metabolites were assessed at ages 20 and 24 years. Latent profile analysis was used to derive profiles of change in recent substance use. Regression models examined associations with cognitive functioning (attention, working memory, declarative memory, composite score) measured at age 24 using the Cambridge Neuropsychological Test Automated Battery and mental health symptoms assessed at both ages 20 and 24 using the Social Behavior Questionnaire. Results: Among participants with substance use at either time point ( Conclusions: Emerging adults' profiles of change in recent substance use were associated with specific cognitive and mental health risks.

Indexed as

AddictionEcstasyHair toxicologyNeuropsychologyRecreational useSubstance use disorder

Identifiers

PMID42733446
PMCPMC13571240

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.