Evidence map›Paper›PMID 42733413›Full record

ArticleAdvances in radiation oncology2026

A Generalized Software Framework for Consolidation of Radiation Therapy Planning and Delivery Data From Diverse Data Sources.

Yasin Abdulkadir, Justin Hink, Peter Boyle, Dishane Luximon, Justin Pijanowski, Timothy Ritter, Bruce Curran, Min Leu, Nicholas Nickols, Steve P Lee and 9 more

Abstract read
In one paragraph

Article in Advances in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Validating a framework for Pinnacle plan conversion and archival.Journal of applied clinical medical physics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yasin AbdulkadirDepartment of Radiation Oncology, University of California, Los Angeles, California.
Justin HinkDepartment of Radiation Oncology, University of California, Los Angeles, California.
Peter BoyleDepartment of Radiation Oncology, University of California, Los Angeles, California.
Dishane LuximonDepartment of Radiation Oncology, University of California, Los Angeles, California.
Justin PijanowskiDepartment of Radiation Oncology, University of California, Los Angeles, California.
Timothy RitterVirginia Commonwealth University Health System, Department of Radiation Oncology, Richmond, VA.
Bruce CurranVirginia Commonwealth University Health System, Department of Radiation Oncology, Richmond, VA.
Min LeuVA Greater Los Angeles Healthcare System, Department of Radiation Oncology, Los Angeles, CA.
Nicholas NickolsVA Greater Los Angeles Healthcare System, Department of Radiation Oncology, Los Angeles, CA.
Steve P LeeVA Long Beach Healthcare System, Department of Radiation Oncology, Long Beach, CA.
Maria KellyDepartment of Veterans Affairs National Radiation Oncology Program, Richmond, VA.
Byron WilsonOregon Health and Science University, Department of Radiation Medicine, Portland, OR.
Zachary BartonOregon Health and Science University, Department of Radiation Medicine, Portland, OR.
Jatinder R PaltaVirginia Commonwealth University Health System, Department of Radiation Oncology, Richmond, VA.
Rishabh KapoorVirginia Commonwealth University Health System, Department of Radiation Oncology, Richmond, VA.
Reid F ThompsonDepartment of Veterans Affairs National Radiation Oncology Program, Richmond, VA.
Daniel A LowDepartment of Radiation Oncology, University of California, Los Angeles, California.
James M LambDepartment of Radiation Oncology, University of California, Los Angeles, California.
Jack NeylonDepartment of Radiation Oncology, University of California, Los Angeles, California.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Large-scale radiation therapy data sets drive predictive modeling, automated segmentation and planning, and personalized treatment, yet remain fragmented because treatment planning (TPS) and record-and-verify (R&V) systems differ, Digital Imaging and Communications in Medicine (DICOM) implementations are inconsistent, and automated linkage tools are lacking. We developed a generalizable framework that automatically reconstructs complete planning and delivery data sets across diverse clinical environments with minimal manual effort. Methods and Materials: We designed and implemented a software framework capable of automating the collection and integration of radiation therapy data from multiple institutions and TPS/R&V combinations. The system begins with Radiation Therapy Treatment Records and recursively traces unidirectional DICOM references to retrieve linked radiation therapy treatment plans, doses, structure sets, planning images, image registrations, and associated diagnostic images. Core components of the framework include automated DICOM queries, secure data transfer, integrity verification, linkage mapping, and detailed logging. To support diverse environments, we developed custom modules for non-DICOM-compliant systems, file format conversions, and robust error handling. Results: The framework was deployed across 4 institutions using 6 different combinations of TPS and R&V systems. In a focused 2-clinic implementation spanning 11 years of retrospective data, the system successfully processed and integrated data from 6164 patients and 13,871 radiation therapy plans. The pipeline achieved a 99.76% success rate in identifying and linking complete treatment data sets, with an average processing time of 18 minutes per patient, demonstrating its efficiency and scalability in real-world conditions. Conclusions: This automated framework provides a scalable and reliable solution for large-scale aggregation of radiation therapy data. It is compatible with heterogeneous clinical systems, including those lacking DICOM Query/Retrieve support, and overcomes key technical barriers to data integration. By enabling the creation of comprehensive, high-quality data sets, the framework supports advanced research and contributes to the improvement of clinical care in radiation oncology.

Identifiers

PMID42733413
PMCPMC13571137

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.