ArticleClinics (Sao Paulo, Brazil)2026
Cardiovascular risk estimation using the steno type 1 risk engine in Brazilian individuals with type 1 diabetes: a multicenter cross-sectional study.
Article in Clinics (Sao Paulo, Brazil), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo assess the 5- and 10-year Cardiovascular Disease (CVD) risk among Brazilian patients with Type 1 Diabetes (T1D) using the Steno Type 1 Risk Engine (ST1RE), and to evaluate the prevalence of clinical CVD, analyzing traditional and non-traditional risk factors. MATERIAL AND
methodsThis was a cross-sectional multicenter study conducted in 13 public clinics in 11 Brazilian cities, involving 1,760 patients. The ST1RE was used in patients without previous CVD (n = 1,300).
resultsThe prevalence of CVD was 2.1%, with ischemic heart disease being the most common. These patients were older, had higher age at T1D diagnosis, and longer diabetes duration when CVD was diagnosed. According to ST1RE 10-year risk, 70.7% were classified as low, 18.0% as moderate, and 11.3% as high risk without differences regarding sex. A lower use of cardioprotective drugs was noted in patients with moderate/high 10-year ST1RE in relation to guidelines recommendations. Higher age at diagnosis, presence of retinopathy, elevated high-sensitivity C-reactive protein, and uric acid levels were associated to moderate/high ST1RE risk.
conclusionsAlmost 30% of our patients had moderate/high ST1RE risk and were undertreated for CVD risk factors. This highlights the need to establish strategies to improve cardiovascular and diabetes management risk in routine clinical practice.
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