ArticleCureus2026
A Case of Loeys-Dietz Syndrome Treated With Emergency Endovascular Repair for a Ruptured Internal Iliac Artery Aneurysm.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
We report the case of a 38-year-old man with Loeys-Dietz syndrome (LDS) who presented in hemorrhagic shock due to rupture of a right internal iliac artery aneurysm, with contrast-enhanced computed tomography (CT) also revealing multiple aneurysms involving the aortic root, abdominal aorta, and several visceral and pelvic arteries. Because of hemodynamic instability and a history of prior abdominal surgery, open surgical repair was considered high-risk, and emergency endovascular treatment was chosen instead. Coil embolization was performed at the proximal neck of the internal iliac artery, and the distal branch vessel was embolized with a mixture of n-butyl-2-cyanoacrylate (NBCA) and Lipiodol, achieving complete hemostasis without unintended embolization. The patient's hemodynamic status stabilized, and he was discharged ambulatory on postprocedure day 30. Genetic testing subsequently confirmed a missense mutation in transforming growth factor-beta receptor type 1 (TGFBR1), establishing the diagnosis of LDS. This case illustrates that combined NBCA and coil embolization can be an effective and rapid hemostatic strategy for a ruptured internal iliac artery aneurysm in patients with LDS, for whom open repair carries substantial risk.
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