Evidence map›Paper›PMID 42732378›Full record

ArticleDEN open2027

Feature-Based Patterns Associated With Japan NBI Expert Team Type 1 Classification of Serrated Colorectal Lesions: A Post Hoc Decision Tree Analysis.

Taku Sakamoto, Hiroyuki Takamaru, Daizen Hirata, Iwatate Mineo, Yasushi Sano, Hideki Ishikawa, Saito Yutaka, Japan NBI Expert Team (JNET)

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Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Taku SakamotoDepartment of Gastroenterology Institute of Medicine University of Tsukuba Tsukuba Japan.
Hiroyuki TakamaruEndoscopy Division National Cancer Center Hospital Tokyo Japan.
Daizen HirataGastrointestinal Center Sano Hospital Kobe Japan.
Iwatate MineoGastrointestinal Center Sano Hospital Kobe Japan.
Yasushi SanoGastrointestinal Center Sano Hospital Kobe Japan.
Hideki IshikawaDepartment of Molecular-Targeting Prevention Kyoto Prefectural University of Medicine Kyoto Japan.
Saito YutakaEndoscopy Division National Cancer Center Hospital Tokyo Japan.
Japan NBI Expert Team (JNET)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Japan NBI Expert Team (JNET) Type 1 classification is used for optical characterization of colorectal lesions with magnifying NBI, but reported Type 1-related findings may differ between readers when assessing serrated lesions. This small-scale post hoc reader-based study explored reported feature-classification patterns associated with JNET Type 1 selection among serrated colorectal lesions and compared them between expert and non-expert endoscopists. Methods: We analyzed de-identified data from two web-based image-interpretation studies using the same colorectal lesion image dataset. Thirteen histologically confirmed serrated lesions (11 sessile serrated lesions [SSLs] and two hyperplastic polyps [HPs]) assessed by 27 expert and 49 non-expert Japanese endoscopists were included. Simplified JNET responses were dichotomized as Type 1 versus non-Type 1. Classification and regression tree analysis was used to visualize associations between this outcome and predefined features, including Type 1-supportive findings and an anti-Type 1 composite variable. Variability was assessed using entropy. Results: In the expert and non-expert core models, the root splits were anti-Type 1 findings and regular dark or white spots, respectively. These root splits were stable in leave-one-reader-out analyses, but the non-expert root split changed to anti-Type 1 findings after excluding unassessable responses. Median entropy was lower among experts than non-experts (0.229 vs. 0.954). Conclusions: This exploratory post hoc decision tree analysis suggested relatively stable expert-associated feature-classification patterns, whereas non-expert patterns were influenced by the treatment of unassessable responses. These findings reflect exploratory associations in Type 1 assignment, not cognitive decision sequences, SSL-HP differentiation, or a validated diagnostic algorithm.

Indexed as

colonic polypscolonoscopydecision treesnarrow band imagingserrated lesions

Identifiers

PMID42732378
PMCPMC13570418

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.