ArticleBone reports2026
Children with unilateral spastic cerebral palsy have smaller and weaker tibias in the spastic limb compared to the non-spastic limb.
Article in Bone reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Cerebral palsy (CP) is associated with poor bone architecture. It is unclear if abnormal bone architecture is localized to the area affected by spasticity and whether these deficiencies are dependent on physical activity. This study aimed to examine differences in tibial bone architecture between the spastic and non-spastic limbs in children with unilateral spastic CP and the association between physical activity habits with spastic limb bone architecture. Twenty-four ambulatory children with CP (13 females, 11 males; 7.8 ± 1.7 years) completed bilateral high-resolution peripheral quantitative computed tomography (HR-pQCT) at the distal tibia metaphysis. The frequency of participation (FPS), bone specific physical activity questionnaire (BPAQ), and dynamic participation survey (DPS) were used to assess physical activity habits. Differences between limb architecture were assessed with paired
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