Evidence map›Paper›PMID 42732262›Full record

ArticleStem cells international2026

Early-Onset Preeclampsia-Derived hUC-MSCs Exhibit Accelerated Initial Culture Kinetics Without Sustained Growth Advantage: A Comparative In Vitro Study.

İbrahim Alptekin, Bilge Alptekin, Ezel Erkan, Ferda Topal Celikkan, Derya Uyan Hendem, Dilek Şahin, Alp Can

Abstract read
In one paragraph

Article in Stem cells international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

İbrahim AlptekinDepartment of Histology and Embryology, Ankara University School of Medicine, Ankara, Türkiye, ankara.edu.tr.ORCID https://orcid.org/0000-0003-0622-6687
Bilge AlptekinDepartment of Histology and Embryology, Ankara University School of Medicine, Ankara, Türkiye, ankara.edu.tr.ORCID https://orcid.org/0000-0001-5061-2775
Ezel ErkanThe Graduate School of Health Sciences of Ankara University, Ankara, Türkiye.ORCID https://orcid.org/0009-0003-2703-0138
Ferda Topal CelikkanDepartment of Histology and Embryology, Ankara University School of Medicine, Ankara, Türkiye, ankara.edu.tr.ORCID https://orcid.org/0000-0002-8254-0558
Derya Uyan HendemPrivate Practice, Perinatology and Obstetrics and Gynecology, Diyarbakir, Türkiye.ORCID https://orcid.org/0000-0003-1866-7295
Dilek ŞahinAnkara Bilkent City Hospital, Ankara, Türkiye.ORCID https://orcid.org/0000-0001-8567-9048
Alp CanDepartment of Histology and Embryology, Ankara University School of Medicine, Ankara, Türkiye, ankara.edu.tr.ORCID https://orcid.org/0000-0002-5393-6115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia (PE) is a pregnancy-related disorder associated with significant maternal and fetal morbidity, and intrauterine conditions may influence the biological behavior of human umbilical cord (UC)-derived mesenchymal stem cells (hUC-MSCs). However, comparative data between early-onset PE (EOPE) and late-onset PE (LOPE) remain limited. This study aimed to compare the in vitro growth kinetics of hUC-MSCs derived from pregnancies complicated by EOPE and LOPE. In this comparative in vitro study, UC samples (

Indexed as

cell cultureearly-onset preeclampsia (EOPE)human umbilical cord-derived mesenchymal stromal cells (hUC-MSCs)late-onset preeclampsia (LOPE)population doubling time

Identifiers

PMID42732262
PMCPMC13570448

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.