Evidence map›Paper›PMID 42732248›Full record

ArticleClinical case reports2026

From Undifferentiated Connective Tissue Disease to Common Variable Immunodeficiency: A Novel NFKB1 Mutation in a Pediatric Case.

Yu-Jie Hu, Sheng Hao, Dan Feng, Bing-Xue Huang, Wen-Yan Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Jie HuDepartment of Nephrology, Rheumatology and Immunology, School of Medicine, Shanghai Children's Hospital Jiao Tong University Shanghai China.ORCID https://orcid.org/0000-0002-8035-7979
Sheng HaoDepartment of Nephrology, Rheumatology and Immunology, School of Medicine, Shanghai Children's Hospital Jiao Tong University Shanghai China.
Dan FengDepartment of Nephrology, Rheumatology and Immunology, School of Medicine, Shanghai Children's Hospital Jiao Tong University Shanghai China.
Bing-Xue HuangDepartment of Nephrology, Rheumatology and Immunology, School of Medicine, Shanghai Children's Hospital Jiao Tong University Shanghai China.ORCID https://orcid.org/0009-0009-2838-8872
Wen-Yan HuangDepartment of Nephrology, Rheumatology and Immunology, School of Medicine, Shanghai Children's Hospital Jiao Tong University Shanghai China.ORCID https://orcid.org/0000-0002-2197-0781

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Common variable immunodeficiency (CVID) may initially manifest as undifferentiated connective tissue disease (UCTD) in the absence of recurrent infections or hypogammaglobulinemia. In patients presenting with warning signs, neither older age nor normal immunoglobulin levels should preclude consideration of CVID; early genetic testing is recommended.

Indexed as

child‐patientcommon variable immunodeficiencyNFKB1undifferentiated connective tissue disease

Identifiers

PMID42732248
PMCPMC13569880

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.