Evidence map›Paper›PMID 42732061›Full record

ArticleBMC anesthesiology2026

Post-traumatic stress disorder following intensive care for COVID-19: a single-center retrospective follow-up study.

Carsten Zeiner, Pascal D Schmitt, Julius J Weise, Torben M Rixecker, Robert Bals, Philipp M Lepper

Abstract read
In one paragraph

Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Carsten ZeinerDepartment of Internal Medicine V Pneumology, Allergology and Critical Care Medicine, Faculty of Medicine, Saarland University, Kirrbergerstraße 100, Homburg/Saar, 66421, Germany. carsten.zeiner@uni-saarland.de.
Pascal D SchmittDepartment of Internal Medicine V Pneumology, Allergology and Critical Care Medicine, Faculty of Medicine, Saarland University, Kirrbergerstraße 100, Homburg/Saar, 66421, Germany.
Julius J WeiseFaculty of Medicine, Institute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University, Homburg/Saar, Germany.
Torben M RixeckerDepartment of Internal Medicine V Pneumology, Allergology and Critical Care Medicine, Faculty of Medicine, Saarland University, Kirrbergerstraße 100, Homburg/Saar, 66421, Germany.
Robert BalsDepartment of Internal Medicine V Pneumology, Allergology and Critical Care Medicine, Faculty of Medicine, Saarland University, Kirrbergerstraße 100, Homburg/Saar, 66421, Germany.
Philipp M LepperDepartment of Internal Medicine, Pneumology and Intensive Care Medicine, University Hospital OWL Campus Bethel and University of Bielefeld, Bielefeld, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSevere COVID-19 frequently required prolonged intensive care, including mechanical ventilation or extracorporeal membrane oxygenation (ECMO). Survivors of such critical illness may develop post-traumatic stress disorder (PTSD).

methodsWe conducted a single-center retrospective follow-up study of COVID-19 ICU survivors at Saarland University Medical Center, Germany, assessing ICD-11 trauma-related disorders using the validated International Trauma Questionnaire (ITQ) and analyzing associations with clinical factors.

resultsOf 110 eligible patients, 42 (38.2%) valid datasets were obtained. The overall prevalence of ICD-11 trauma-related disorders (PTSD or CPTSD) was 23.8% (95% CI 12.1-39.5%; n = 10), with PTSD diagnosed in 6 participants (14.3%; 95% CI 5.4-28.5%) and CPTSD in 4 participants (9.5%; 95% CI 2.7-22.6%). No statistically significant associations were found for any of the examined variables. Exploratory subgroup analyses revealed numerically higher rates of trauma-related disorders in patients with prior psychiatric treatment (40.0% vs. 21.6%), ECMO therapy (33.3% vs. 16.7%), or renal replacement therapy (50.0% vs. 17.6%); however, these findings should be interpreted with caution given the limited sample size.

conclusionsNearly one quarter of COVID-19 ICU survivors met the diagnostic criteria for PTSD or CPTSD, a prevalence comparable to that observed in other critically ill populations. No statistically significant associations were identified, and the observed subgroup differences should be regarded as exploratory and hypothesis-generating. The reported prevalence of PTSD/CPTSD highlights the potential value of systematic screening for trauma-related disorder and the integration of psychological support into post-ICU care. Larger prospective multicenter studies are needed to confirm these findings and further characterize potential risk factors.

trial registrationThe study was reviewed and approved by the Ethics committee of the Medical Association of Saarland (Number 98/22).

Indexed as

COVID-19Critical CareStress Disorders, Post-TraumaticAdultAgedExtracorporeal Membrane OxygenationFemaleFollow-Up StudiesGermanyHumansMaleMiddle AgedRespiration, ArtificialRetrospective StudiesSurvivorsCOVID-19Critical illnessExtracorporeal membrane oxygenationFollow-upMental healthPost-traumatic stress disorderRisk factors

Identifiers

PMID42732061
PMCPMC13570528

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.