Evidence map›Paper›PMID 42730923›Full record

ArticlePlanta2026

Unique N-acetyl-L-glutamate kinase of Prasinoderma coloniale: new features of an old enzyme.

Vladislav Statinov, Tatiana Lapina, David Musaelyan, Elena Ermilova

Abstract read
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In one paragraph

Article in Planta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Vladislav StatinovBiological Faculty, Saint-Petersburg State University, Universitetskaya Emb 7/9, St. Petersburg, 199034, Russia.
Tatiana LapinaBiological Faculty, Saint-Petersburg State University, Universitetskaya Emb 7/9, St. Petersburg, 199034, Russia.
David MusaelyanBiological Faculty, Saint-Petersburg State University, Universitetskaya Emb 7/9, St. Petersburg, 199034, Russia.
Elena ErmilovaBiological Faculty, Saint-Petersburg State University, Universitetskaya Emb 7/9, St. Petersburg, 199034, Russia. e.ermilova@spbu.ru.ORCID http://orcid.org/0000-0003-0800-5933

Funding

Saint Petersburg State University 119992468
6 · The paper itself

Abstract

MAIN

conclusionN-Acetyl-L-glutamate kinase of Prasinoderma coloniale is an example of an evolutionary hack that allows this alga survival without the protein PII. N-Acetyl-L-glutamate kinase (NAGK) catalyzes the phosphorylation of N-acetyl-L-glutamate to N-acetyl-L-glutamyl-phosphate, which is the rate-limiting step in the ornithine/arginine biosynthesis pathway. In cyanobacteria and Archaeplastida, NAGK activity is strictly regulated by the end product, arginine (Arg), and is controlled by the PII signaling protein. During evolution, Prasinoderma coloniale, a phytoplankton species from an early-branching lineage within the Archaeplastida, lost the gene encoding PII protein. PcNAGK shows a unique feature: it has evolved to be an enzyme that is virtually insensitive to intracellular levels of Arg with an IC

Indexed as

ChlorophytaPhosphotransferases (Carboxyl Group Acceptor)Amino Acid SequenceArgininePhylogenyPII Nitrogen Regulatory Proteinsacetylglutamate kinaseArgininePhosphotransferases (Carboxyl Group Acceptor)PII Nitrogen Regulatory ProteinsArginine biosynthesisMetabolic adaptationN-acetyl-L-glutamate kinasePrasinoderma coloniale

Identifiers

PMID42730923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.