Evidence map›Paper›PMID 42730902›Full record

ReviewReviews in endocrine & metabolic disorders2026

Time-efficient exercise strategies to reduce visceral adipose tissue in children and adolescents with overweight or obesity: evidence from a pairwise and network meta-analysis.

Chaofan Chen, Xiaoke Chen, Isaac A Chávez-Guevara, Francisco J Amaro-Gahete, Yanwei You, Qing Yi, Zhiyuan Tan, Yang Jiang, Mengmeng Ji, Carlo Castagna and 4 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chaofan Chen *Division of Sports Science and Physical Education, Tsinghua University, Beijing, 100084, China.
Xiaoke Chen *Division of Sports Science and Physical Education, Tsinghua University, Beijing, 100084, China.
Isaac A Chávez-GuevaraFaculty of Sports Ensenada, Autonomous University of Baja California, Ensenada, Baja California, Mexico.
Francisco J Amaro-GaheteDepartment of Physiology, Faculty of Medicine, University of Granada, Granada, Spain.
Yanwei YouDivision of Sports Science and Physical Education, Tsinghua University, Beijing, 100084, China.
Qing YiDivision of Sports Science and Physical Education, Tsinghua University, Beijing, 100084, China.
Zhiyuan TanFaculty of Sport and Physical Education, University of Belgrade, Blagoja Parovića 156, Belgrade, 11000, Serbia.
Yang JiangSchool of Physical Education, Yunnan Normal University, Kunming, Yunnan, China.
Mengmeng JiDivision of Public Health Sciences, Department of Surgery, Washington University in St. Louis, St. Louis, MO, USA.
Carlo CastagnaDepartment of Education and Sport Sciences, Pegaso Telematic University, Naples, Italy.
Susana PóvoasDepartment of Sports Science and Clinical Biomechanics, SDU Sport and Health Sciences Cluster (SHSC), University of Southern Denmark, Odense, 5230, Denmark.
Danijela GasevicSchool of Public Health and Preventive Medicine, Faculty of Medicine, Nursing & Health Sciences, Monash University, Victoria, 3004, Australia.
Jianxiu LiuDivision of Sports Science and Physical Education, Tsinghua University, Beijing, 100084, China. liujianxiu@mail.tsinghua.edu.cn.
Xindong MaDivision of Sports Science and Physical Education, Tsinghua University, Beijing, 100084, China. maxd@mail.tsinghua.edu.cn.

Funding

National Social Science Fund of China 25CTY033
6 · The paper itself

Abstract

High-quality meta-analyses focusing specifically on exercise-induced changes in visceral adipose tissue (VAT) in children and adolescents with overweight or obesity (CAO) remain limited. This study compared the relative effects of four common exercise modalities and identified potentially promising strategies for reducing VAT in CAO. Seven databases were searched from inception to September 2025 for studies comparing exercise interventions with controls on VAT in CAO. A multi-level and network meta-analysis were performed to estimate effect sizes and rank exercise modalities. Subgroup and meta-regression analyses explored the influence of various moderators. Risk of bias, publication bias, sensitivity, and certainty of evidence were also assessed. A two-dimensional analysis was conducted to compare efficacy, acceptability, and time efficiency across different exercise modalities. A total of 34 studies and 2060 participants were included. High-intensity interval training (HIIT) showed the most pronounced effect (g = -0.78 [-1.24 to -0.32]) on reducing VAT, followed by aerobic combined resistance training (g = -0.65 [-1.01 to -0.29]) and aerobic exercise (g = -0.42 [-0.63 to -0.21]), while resistance training showed no significant benefit. Exploratory subgroup analyses suggested greater VAT reductions in interventions conducted at least three times per week and lasting 12 weeks or longer. Meta-regression identified study-level associations of VAT reduction with baseline BMI, changes in cardiorespiratory fitness, and sex distribution. Network and two-dimensional analyses suggested that HIIT had the highest ranking probability for VAT reduction and was associated with the shortest weekly intervention time and the lowest dropout rate, although the certainty of evidence was low to very low. The effects of different exercise modalities on VAT vary, with intervention efficacy influenced by duration and individual characteristics. HIIT may be a promising and time-efficient exercise option for reducing VAT in CAO; however, this finding should be interpreted cautiously given the low to very low certainty of evidence.

Indexed as

AdolescentsChildrenExerciseMeta-analysisObesityVisceral adipose tissue

Identifiers

PMID42730902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.