ArticleProtoplasma2026
Loop-mediated isothermal amplification (LAMP) for quality control of Coscinium fenestratum: a colorimetric platform for detecting Anamirta cocculus adulteration.
Article in Protoplasma, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Coscinium fenestratum (Gaertn.) Colebr., commonly known as tree turmeric, is a critically endangered medicinal plant extensively used in Ayurveda and Siddha systems for treating metabolic disorders and various infectious diseases. Due to overexploitation and habitat loss, Coscinium fenestratum faces severe conservation threats, resulting in a scarcity of authentic raw material and frequent adulteration with morphologically similar species such as Anamirta cocculus. The present study reports the development and validation of an internal transcribed spacer (ITS) based loop-mediated isothermal amplification (LAMP) assay for rapid authentication of C. fenestratum and sensitive detection of A. cocculus adulteration. Species specific LAMP primers were designed targeting the variable regions of ITS sequence, and assay optimization identified 7 mM MgSO
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