Evidence map›Paper›PMID 42730760›Full record

ArticleLangenbeck's archives of surgery2026

Outcome after renal transplantation utilizing octogenarian donors- retrospective single-center analysis within the Eurotransplant region.

Dennis Kleine-Doepke, Oliver Beetz, Christian Hinze, Ulrich Zwirner, Cornelius van Beekum, Philipp Felgendreff, Markus Quante, Ulf Kulik, Moritz Schmelzle, Gerrit Grannas

Abstract read
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Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dennis Kleine-DoepkeDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Oliver BeetzDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Christian HinzeDepartment of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.
Ulrich ZwirnerDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Cornelius van BeekumDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Philipp FelgendreffDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Markus QuanteDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Ulf KulikDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Moritz SchmelzleDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Gerrit GrannasDepartment of General, Visceral and Transplant Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Grannas.Gerrit@mh-hannover.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA severe shortage of donors and organs remains the primary challenge in modern transplantation medicine. For kidney transplantation, prolonged time on the waiting list increases morbidity and mortality, particularly among elderly patients. Dedicated allocation initiatives, such as the Eurotransplant Senior Program (ESP), were established to shorten waiting times, and previous age limits for organ acceptance were raised to expand the donor pool for this specific patient population.

methodsThis retrospective study evaluated all patients who received a kidney graft from an octogenarian donor between January 2006 and September 2023. Key outcomes assessed included patient survival, graft survival, and graft function.

resultsA total of 71 kidney transplantations were included. Primary non-function occurred in five patients, and nine patients experienced delayed graft function. The 5-year recipient survival rate was 68.8%, and the 5-year death-censored graft survival rate was 65.3%. Graft function, assessed via median serum creatinine levels, remained stable throughout the follow-up period, although median creatinine values did not return to the normal range.

conclusionsFollowing meticulous donor selection, allocating kidney grafts from donors aged 80 years or older represents a viable strategy to expand the donor pool for ESP patients.

Indexed as

Donor SelectionKidney TransplantationTissue DonorsAged, 80 and overEuropeFemaleGraft SurvivalHumansMaleRetrospective StudiesSurvival RateTreatment OutcomeEurotransplant senior programGraft functionKidney transplantationOctogenarian donors

Identifiers

PMID42730760
PMCPMC13570896

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