ArticlePulmonary circulation2026
Validation of Tricuspid Annular Displacement by Tissue Doppler in Pulmonary Hypertension.
Article in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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8 authors.
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Abstract
Tricuspid annular plane systolic excursion (TAPSE) is primarily measured using motion-mode (M-mode) echocardiography. However, image resolution doesn't always provide clear visualization. In these cases, tissue Doppler imaging (TDI) may offer a valuable alternative for right ventricular assessment. To validate TDI-derived TAPSE (TAPSE-TDI) against M-mode TAPSE and compare their diagnostic utility for right heart catheterization-confirmed pulmonary hypertension(PH). We analyzed 304 healthy volunteers and 310 PH patients in a case-control study. M-mode TAPSE and TAPSE-TDI were measured in the RV-focused apical four-chamber view. TAPSE-TDI was calculated by averaging the systolic and diastolic signals from the lateral tricuspid annulus. Agreement between methods was quantified using bias, percentile precision, and intra-class coefficient (ICC). The dependence of annular motion on body size, sex, and heart rate was evaluated with weighted regression. We assessed PH discrimination using receiver operating curve (ROC) analysis, comparing TAPSE, TAPSE-TDI, and RV TDI peak systolic velocity (s'). Thresholds were further tested using Classification and Regression Tree (CART) analysis. TAPSE-TDI demonstrated a strong linear relationship with TAPSE (
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