ArticleFrontiers in nutrition2026
Prevalence of hyperuricemia and its associations with hyperinsulinemia and hepatic injury among adolescents with obesity in Guangxi, China.
Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the prevalence of hyperuricemia (HUA) in adolescents with obesity in Guangxi, southern China, and explore its associations with hyperinsulinemia and hepatic injury. Methods: A total of 200 adolescents with obesity aged 10-18 years who visited the Children and Adolescents Weight Management Center of Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region from May to December 2025 were enrolled. According to the Results: The prevalence of HUA was 44.50% (89/200), with 47.59% (69/145) in males and 36.36% (20/55) in females. Univariate analysis showed significant between-group differences in age, body mass index z-score (BMIZ), low-density lipoprotein cholesterol (LDL-C), fasting insulin, alanine aminotransferase (ALT), dyslipidemia, and hyperinsulinemia (all Conclusion: HUA is highly prevalent among adolescents with obesity in Guangxi. Older age, hyperinsulinemia, and elevated ALT are independently associated with HUA risk. These findings highlight the importance of comprehensive metabolic management, including insulin sensitivity and liver function assessment, in this high-risk population.
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