ArticleJPRAS open2026
The role of nanofat membranes in inhibiting bacterial growth: An in vitro analysis.
Article in JPRAS open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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Abstract
Introduction: Wound healing is a major clinical concern, particularly in chronic wounds complicated by bacterial colonization, which delays healing and increases the risk of severe complications. Platelet-rich fibrin (PRF) and nanofat are promising regenerative biomaterials with potential antibacterial properties. This study evaluates the antibacterial efficacy of nanofat membranes, including nanofat-PRF and microfat-nanofat-PRF, against clinically relevant bacterial strains. Materials and methods: An experimental study was conducted using samples from five healthy volunteers. Nanofat membranes with varying ratios (nanofat:PRF 1:1, 1:2, 2:1, and microfat-nanofat-PRF 1:1:1) were prepared using autologous fat and injectable PRF. Antibacterial activity was tested against Results: The membranes exhibited substantial antibacterial activity against all tested strains, with Conclusions: Nanofat membranes demonstrated notable antibacterial activity against major clinical pathogens, suggesting synergistic effects between adipose-derived and platelet components. Further studies with larger samples are warranted to identify the active antibacterial factors and optimize formulations for wound healing and infection control.
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