ArticleJournal of International Society of Preventive & Community Dentistry
Salivary Calcium and Albumin as Biomarkers of Oral Dryness in Postmenopausal Women: A Case-Control Analysis.
Article in Journal of International Society of Preventive & Community Dentistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Menopause-associated hypoestrogenism significantly alters oral homeostasis, often leading to xerostomia. Although salivary calcium and albumin are indicators of mineral turnover and mucosal permeability, their specific correlation with subjective and objective oral dryness in postmenopausal cohorts requires further elucidation. The aim was to evaluate salivary calcium and albumin levels in postmenopausal women with and without oral dryness and to compare these findings with the clinical symptoms. Methods: This case-control study included three groups ( Results: Group III (postmenopausal women with oral dryness) had significantly higher salivary calcium and albumin levels than both Group II and Group I ( Conclusion: Elevated salivary calcium and albumin levels serve as significant biochemical markers for oral dryness in postmenopausal women. These findings suggest that increased mucosal permeability and altered mineral transport are key physiological features of the menopausal oral cavity, necessitating targeted preventive dental care.
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