Evidence map›Paper›PMID 42730065›Full record

ArticleCureus2026

A Shared, Practical, Interactive Curriculum for Extracorporeal Membrane Oxygenation (SPICE): Time to SPICE It Up!

Lauren Alessi, Divya Gupta, Ashley Siems, Peggy Han

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lauren AlessiDepartment of Pediatric Critical Care Medicine, Corewell Health Helen DeVos Children's Hospital, Michigan State University College of Human Medicine, Grand Rapids, USA.
Divya GuptaDepartment of Pediatric Critical Care Medicine, Children's National Hospital, Washington, D.C., USA.
Ashley SiemsDepartment of Pediatric Critical Care Medicine, Johns Hopkins All Children's Hospital, St. Petersburg, USA.
Peggy HanDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, Stanford University School of Medicine, Lucile Packard Children's Hospital, Palo Alto, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Extracorporeal membrane oxygenation (ECMO) is a complex but infrequently used technology that plays a crucial role for patients experiencing cardiopulmonary failure. Formal ECMO education remains inconsistent, with considerable variability in structure and availability. We aimed to implement a shared, practical, and interactive curriculum on ECMO or "SPICE" across multiple institutions. Methods Educators collaborated across four different institutions developing an ECMO curriculum that consisted of 15 educational sessions including 10 simulated ECMO emergencies. Three institutions deployed the curriculum over an academic year and a fourth served as a control site. Feasibility was assessed with the percentage of curriculum completed at each site. Effectiveness was assessed by qualitative analysis of fellow response to learning as well as pre- and post- test knowledge assessment and learner confidence. Results The curriculum was successfully executed at all three sites, making it a feasible curriculum for any training program that has a simulation center and access to ECMO equipment. Fellows answered an average of 68% (± 10%) correct on medical knowledge assessment pre-curriculum and 64% (± 5%) post-curriculum, which was not statistically different. Average confidence in answers was greater in the SPICE post-curriculum survey versus the control group (2.2±0.2 vs.1.8±0.3, p=0.03). Themes that emerged from the qualitative analysis showed that learners benefited in six domains including self-confidence, knowledge, resources, decision-making, skill practice, and communication. Conclusions SPICE is a novel, standardized, and feasible way to teach ECMO skills and increase trainee confidence through hands-on learning.

Indexed as

critical care medicineextracorporeal life support (ecls)extracorporeal membrane oxygenation (ecmo)fellowshippediatricspeer mentorshipsimulationveno-arterial extracorporeal membrane oxygenation (va ecmo)veno-venous extracorporeal membrane oxygenation (vv ecmo)

Identifiers

PMID42730065
PMCPMC13568052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.