Evidence map›Paper›PMID 42729941›Full record

ArticleACS materials Au2026

DNA/RNA Hybrid Hairpin Gold Nanobeacons Targeting miR-31 Reprogram Invasion in Lung Cancer and Remodel Tumor Histo-Architecture

Diana P Sousa, Jhenifer Oliveira, Catarina F Martins, João Conde

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS materials Au, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Diana P SousaNOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.ORCID https://orcid.org/0000-0003-3474-5417
Jhenifer OliveiraNOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.
Catarina F MartinsNOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.
João CondeNOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.ORCID https://orcid.org/0000-0001-8422-6792

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Readout-enabled delivery of anti-microRNA (miRNA) therapeutics remains a bottleneck for translating RNA nanomedicine against invasion and metastasis. We report ∼60 nm PEG-gold nanobeacons bearing a Cy3-labeled anti-miR-31-5p hairpin and establish a chemistry-to-phenotype pipeline spanning physicochemical control, cellular trafficking, functional phenotyping, miR-31 kinetics, transcriptomics, and histology-only

Indexed as

endosomal escapegold nanoparticleinvasionlung cancermicroRNAmolecular beacon

Identifiers

PMID42729941
PMCPMC13564150

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.