Evidence map›Paper›PMID 42729851›Full record

ArticleACS omega2026

Early-Stage Screening of Piperonylic Acid Analogues and Their Salts as Synergists for the Class of Pyrethroid Insecticides.

Ramana Pydi, Alexander Wolf, Jennifer Bernard, Christoph Zutz, Birgit Bromberger, Anita Sosnowska, Szymon Zdybel, Tomasz Puzyn, Rolf Breinbauer, Patrick-Julian Mikuni-Mester

Abstract read
In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ramana PydiCentre for Food Science and Veterinary Public Health, Clinical Department for Farm Animals and Food System Science, University of Veterinary Medicine Vienna, Veterinaerplatz 1 Vienna 1210, Austria.ORCID https://orcid.org/0009-0002-8106-661X
Alexander WolfInstitute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, Graz 8010, Austria.
Jennifer BernardKwizda Agro GmbH, Universitätsring 6, Vienna 1010, Austria.
Christoph ZutzKwizda Agro GmbH, Universitätsring 6, Vienna 1010, Austria.
Birgit BrombergerCentre for Food Science and Veterinary Public Health, Clinical Department for Farm Animals and Food System Science, University of Veterinary Medicine Vienna, Veterinaerplatz 1 Vienna 1210, Austria.
Anita SosnowskaQSAR Lab, Grunwaldzka Ave, 103A, Gdansk 80-244, Poland.ORCID https://orcid.org/0000-0003-3288-4309
Szymon ZdybelQSAR Lab, Grunwaldzka Ave, 103A, Gdansk 80-244, Poland.
Tomasz PuzynQSAR Lab, Grunwaldzka Ave, 103A, Gdansk 80-244, Poland.
Rolf BreinbauerInstitute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9, Graz 8010, Austria.ORCID https://orcid.org/0000-0001-6009-7359
Patrick-Julian Mikuni-MesterCentre for Food Science and Veterinary Public Health, Clinical Department for Farm Animals and Food System Science, University of Veterinary Medicine Vienna, Veterinaerplatz 1 Vienna 1210, Austria.ORCID https://orcid.org/0000-0002-3193-4987

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents an early-stage screening of piperonylic acid analogues and their salts as synergists for the class of pyrethroid insecticides. Using the carbonate-based ionic liquid synthesis (CBILs) method, we synthesized 32 potential synergists from 4 piperonylic acid analogues in a one-step process and experimentally determined general toxicity parameters and synergistic activity in comparison with the commercial synergist piperonyl butoxide (PBO).

Identifiers

PMID42729851
PMCPMC13563995

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.